'*'"March,?m""  }     Lcaves  of  Eupatorium  Furpureum.  121 
red  color,  and  was  precipitated  on  boiling.  2.  Its  lead  salt,  when 
heated  with  AS2O3,  gave  the  kakodyl  reaction.  3.  The  free  acid 
caused  the  formation  of  white  fumes  with  NH4OH. 
VI.  Bviyrio  add. — Was  detected  by  its  odor,  and  exists  in  very- 
small  amount. 
The  oil  having  a  neutral  reaction,  these  acids  probably  exist  as 
compound  ethers;  but  are  present  in  small  amount  only. 
ANALYSIS  OF  THE  LEAVES  OF  EUPATORIUM 
PURPUREUM. 
By  Frank  M.  Siggins. 
A  contribution  from 'the  Chemical  Laboratory  of  the  Philadelphia  College  of 
Pharmacy. 
Read  at  the  Pharmaceutical  Meeting,  February  21. 
Fifty  grams  of  the  drug  in  No.  60  powder  were  exhausted  with, 
petroleum  ether,  the  solid  extract  of  which  amounted  to  6*99  per  cent, 
of  the  weight  of  the  drug.  This  extract  had  a  pale  greenish  color,, 
with  the  odor  of  the  drug,  and  an  insipid,  greasy  taste.  On  heating 
in  an  air-bath  at  110^  C.  it  lost  '186  per  cent,  of  its  weight,  represent- 
ing the  volatile  portion.  It  was  slightly  soluble  in  cold  alcohol,  and 
wholly  so  in  hot  alcohol,  but  precipitated  on  cooling.  On  filtering 
this  solution  and  allowing  it  to  evaporate  spontaneously,  a  white 
granular  wax  was  obtained  which  was  not  examined. 
The  drug  after  thorough  evaporation  of  the  petroleum  was  exhausted 
with  ether.  The  solution  thus  obtained  had  a  bright-green  color  by 
transmitted  light,  but  brownish-red  by  reflected  light,  showing  abund- 
ant evidence  of  chlorophyll.  The  solid  extract  obtained  with  the 
ether  amounted  to  2-97  per  cent,  of  the  weight  of  the  drug.  This 
extract  had  a  dark-green  or  blackish-green  color,  was  hard  when  cold^ 
but  became  soft  at  80°  C. ;  was  insoluble  in  cold  water,  but  partly  so 
in  hot  water,  to  which  it  imparted  its  bitter  taste,  and  which  the  water 
retained  on  cooling.  With  this  aqueous  solution  potassio-mercuric 
iodide  gave  no  precipitate,  but  potassium  tri-iodide  gave  a  bulky 
brownish-red  precipitate,  which  slowly  changed  to  a  light-yellow  and 
indicated  the  probable  presence  of  an  alkaloid;  other  reactions,  how- 
ever, showed  that  this  bitter  principle  is  not  an  alkaloid  but  a  glucoside. 
The  drug  was  then  exhausted  with  alcohol,  to  which  it  yielded  an 
