^""'lugl'Sst^""'}      Practical  Notes  from  Various  Sources.  407 
Dangeks  of  Antipyrin. — Dr.  Raoiilt  {Le  Prog,  m^d.,  May 
26,  188$,)  brings  together  some  of  the  cases  in  which  the  use  of  this 
medicament  has  gained  unsatisfactory  results.  Among  the  symptons 
noticed  by  various  observers  were  tumefaction  of  the  face,  urticaria, 
gastric  disturbances,  conjunctival  catarrh,  rapid  pulse,  cardiac  oppression, 
leipothymia, tinnitus,  cerebral  depression  and  one  case  of  amnesia,  lasting 
for  18  hours.  See  states  that  all  "these  accidents  are  not  rare  and  do 
not  possess  all  the  gravity  attributed  to  them."  The  author's  con- 
clusions are,  that  "  it  remains  a  good  medicament  whose  action  is  sure, 
but  should  be  induced  with  circumspection.  Its  employment  will 
certainly  be  more  restrained  when  we  learn  its  effects  and  understand 
better  its  proper  indications  and  dosage.  Then,  we  will  have  no  more 
accidents,  especially  if  we  may  be  absolutely  certain  of  the  purity  of 
the  drug.'' 
PRACTICAL  NOTES  FEOM  VARIOUS  SOURCES.  ' 
By  The  Editor. 
lodotannate  of  Mercury ^  according  to  J.  Nourry  {Bull.  gen.  TMr., 
April  30,)  is  a  soluble  compound  and  does  not  possess  any  apprecia- 
able  metallic  taste.  For  hypodermic  use  a  solution  is  prepared  from 
mercury  0.008  gm.  (J  grain)  ;  iodine  0.03  gm.;  kramero tannic  acid 
0.04  gm. ;  and  glycerin  1  cc. 
Nascent  Silver  iodide  has  been  used  with  success  in  certain  forms 
of  conjunctivitis ;  and  attention  was  again  directed  to  this  form  of 
medication  by  Dr.  Grasselli  (Recueil  dJ  Ophthal.),  who  for  this  pur- 
pose employs  two  solutions,  one  containing  3.56  gm.  of  silver  nitrate, 
and  the  other  3.52  gm.  of  potassium  iodide.  The  salts  are  dissolved 
separately  each  in  3.5  gm.  of  water  and  6.5  gm.  of  glycerin,  and  the 
silver  solution  is  kept  in  a  blue  or  amber  colored  vial.  For  use  two 
drops  of  the  silver  solution  are  mixed  in  a  watch  glass  with  three 
drops  of  the  iodide  solution,  and  this  mixture  is  at  once  applied  by 
means  of  a  camel's  hair  pencil. 
Permanent  solution  of  mercuric  chloride. — To  the  permanent  solu- 
tions mentioned  on  pages  355  and  396  of  our  last  volume,  the  follow- 
ing by  Professor  Kroenlein  of  Zurich  is  added  from  Corr.  Bl.  f.  Schw. 
Aerzte.  Mercuric  cliloride  10,  sodium  chloride  10,  acetic  acid  5,  and 
water  75  parts.    This  10  per  cent,  solution  is  intended  to  be  kept 
