|Am.^our.Pharm.  Characters  of  Antipyrin.  415 
Manganese  Dioxide  and  Dilute  Sulphurie  Acid. — Upon  boiling  a 
rose-colored  liqnid.  Chloroform  removes  a  part  of  the  color,  and, 
evaporated,  leaves  a  brown  residue  that  gives  with  water  a  colorless 
solution  in  which  we  have  found  unaltered  antipyrin. 
Potassium  Bichromate  and  Sulphuric  Acid. — In  the  cold  reduction 
takes  place ;  the  liquid  is  colored  green. 
Strong  Nibnc  Acid. — IN^o  change  takes  place  in  the  cold  if  the  acid 
be  free  from  nitrous  vapors ;  if  it  contain  traces  the  liquid  is  colored 
green.  With  solid  antipyrin,  if  heat  be  applied,  nitric  acid  gives  rise 
to  a  violent  detonation. 
Solution  of  Chloride  of  Lime. — In  the  cold,  no  change ;  with  heat 
an  energetic  reaction,  a  brick-red  precipitate  being  formed  and  the 
liquid  colored  yellow. 
Sodium  Hypochlorite. — In  the  cold,  no  change ;  with  heat,  a  yellow 
coloration,  but  no  precipitate. 
Sodium  Hypohromite. — With  a  concentrated  solution  of  antipyrin  a 
white  precipitate  in  the  cold,  turning  yellow  on  the  application  of 
heat,  a  separation  taking  place  at  the  same  time  in  the  mass  of  the  liquid 
of  small  drops  of  a  brown  liquid  having  an  empyreumatic  odor.  In 
a  one  per  cent,  solution  a  drop  of  the  reagent  causes  a  slight  precipi- 
tate which  redissolves. 
Chlorine  Gas. — White  precipitate.  Chlorine  water  produces  no 
change. 
Bromine  Vapor. — White  precipitate,  becoming  brick  red  at  the 
surface.  Bromine  water  gives  a  light  yellow  precipitate  soluble  when 
heated. 
Iodized  Water. — 2  cc.  of  the  reagent  and  1  cc.  of  one  per  cent, 
solution  of  antipyrin  give  a  persistent  brick-red  precipitate. 
Acid  Nitrate  of  Mercury. — White  precipitate. 
REDUCING  AGENTS. 
Nascent  Hydrogen. — After  six  hours  treatment  the  antipyrin  showed 
no  alteration. 
Nitrous  Acid  or  Nitric  Acid  charged  with  Nitrous  Vapor. — One 
drop  of  the  reagent  and  1  cc.  of  a  one  per  cent,  solution  of  antipyrin 
give  a  beautiful  green  coloration,  still  perceptible  when  diluted  to  1  in 
20,000  ;  when  heated  the  liquid  becomes  purple  red.  One  cc.  of  the 
reagent  and  1  cc.  of  a  one  per  cent,  solution  give  a  golden  yellow 
liquid ;  a  slight  excess  of  the  reagent  causes  the  liquid  to  pass  to 
