Am.  Jour.  Pharm 
Oct.,  1888. 
Mayer^s  Reagent  for  Alkaloids.  491 
Fluid  measures  20  cc.^  and  contains  2  cc,  1  per  cent,  by  vol.,  sulphuric  acid.^ 
Uc.  required. 
X!j  IJ^  U.  1 V  d/ i  c  11 1 . 
3-113 
1  in  500 
-01286 
3-37 
1  in  450 
•0132* 
3-68 
1  in  400 
-0136 
4-13 
1  in  350 
•0138* 
476 
1  in  300 
•0140 
5-67 
1  in  250 
•0141* 
7-04 
l  in  200 
•0142 
The  fluid  measures  30  cc  and  contains  3  cc,  1  per  cent,  by  vol.,  sulphuric  acid. 
Cc  required. 
Dilution. 
Equivalent. 
4-31 
1  in  600 
•0116 
4-67 
1  in  500 
•01286 
5-05 
1  in  450 
•0132* 
5-51 
1  in  400 
•0136 
6-21 
1  in  350 
•0138* 
7-15 
1  in  300 
•0140 
8-50 
1  in  250 
•0141* 
10-56 
1  in  200 
•0142 
Fluid  measures  25  cc.  and  contains  2J  cc,  1  per  cent,  by  volume,  sulphuric  acid. 
Cc  required. 
Dilution. 
Equivalent. 
3-89 
1  in  500 
•01286 
4-21 
1  in  450 
•0132* 
4-59 
1  in  400 
•0136 
5  17 
1  in  350 
•0138* 
5-95 
1  in  300 
-0140 
7-09 
1  in  250 
•0141* 
8-80 
1  in  200 
•0142 
*  In  the  case  of  this  as  in  all  other  alkaloids  mentioned  in  this  paper,  the 
equivalents  marked  with  an  asterisk  are  interpolations,  all  others  were  experi- 
mentally determined. 
^  I  originally  recommended  30  cc.  as  the  dilution  best  suited  for  this  table,, 
intending  thus  to  include  those  drugs  containing  as  much  as  1-2  to  1-3  percent, 
of  alkaloid,  but  as  these  are  rather  the  exception  than  the  rule  the  smaller  vol- 
ume as  pointed  out  by  the  Editor  of  the  Pharm.  Era  is  to  be  preferred.  The 
30  cc.  table,  likewise  a  25  cc  table,  is  however  here  given,  as  they  may  some- 
times be  of  use. 
2  The  volumes  given  at  the  head  of  the  tables  refer  to  the  volume  which  the 
fluid  should  have  at  the  beginning  of  the  titration. 
^  In  practice  reading  is  of  course  only  to  tenths  of  cc  but  in  the  tables- 
readings  have  been  calculated  to  hundredths  for  sake  of  mathematical  exact- 
ness ;  they  may  always  be  read  to  the  nearest  tenth. 
