^"^"octiyiSs^'""^*}      Gleanings  from  the  German  Jommals.  515^ 
men,  if  too  much  acid  be  not  present.  The  non-coagulation  of  the 
peptone  is  due  to  the  sohibility  of  coagulated  albumen  in  lactic  acid ; 
but  on  first  neutralizing  with  ammonia  boiling  will  coagulate  peptone 
solutions.  The  explanation  of  the  same  composition  of  albumen  and 
peptone  is  found  in  the  fact  that  in  the  so-called  purification  of  the 
peptone  the  albumen  was  always  reobtained.  Peptone  will  reduce 
Fehling's  solution,  which  is  of  importance  in  milk  analysis. 
A  distinctive  test  is  the  addition  of  potassium  xanthogenate  ;  with 
albumen  solutions,  a  precipitate  is  only  obtained  on  addition  of  acid, 
while  peptone  solutions,  being  acid,  give  a  precipitate  at  once. — 
Pharm.  Centrlh.,  1888,  395. 
Tasteless  Quinine  Tannate  is  made  as  follows  :  Quinine  sulphate 
40  parts  is  dissolved  in  distilled  water  1200  parts  with  aid  of  the  least 
possible  quantity  of  dilute  sulphuric  acid,  filtered  and,  with  continued 
stirring,  a  solution  of  80  parts  tannic  acid  in  560  parts  distilled  water 
added.  After  standing  24  hours,  filter  and  wash  the  precipitate  with 
400  parts  distilled  water ;  by  slight  pressure  remove  the  excess  of  wa- 
ter from  the  precipitate  and  heat  with  200  parts  distilled  water  until 
it  fuses  to  a  transparent  yellowish  resinous  mass  which,  after  cooling, 
is  powdered. — (Hung.  Pharmacop.)  Rdsch.,  1888,  621. 
Chelidonine  has  been  studied  by  Dr.  A.  Henschke,  who  obtained 
0'29  per  cent,  from  the  root  of  Chelidonium  majus.  The  formula  for 
the  crystallized  alkaloid  is  C20H19NO5  +  HgO ;  after  drying  at  100°  it 
melts  at  135°.  It  is  a  tertiary  base  ;  with  alkaline  potassium  perman- 
ganate, the  oxidation  products  are  CO2,  HgCgO^,  CH3!N'H2 ;  with  acid 
permanganate  only  CO2  and  CH3NH2  are  obtained ;  nitric  acid  gives 
rise  to  C02,H2C204,  CH3NH2  and  a  red  resinous  substance  forming  a 
carmine  red  solution  on  addition  of  KOH  or  J^aOH. — Arch,  der 
Pharm,,  1888,  624. 
Cortex  Frangula  and  Cascara  Sagrada. — P.  Schwabe  on  examina- 
tion of  the  former  bark  finds  it  to  contain  two  crystalline  principles, 
emodin,  identical  with  frangulinic  acid,  and  frangulin.  This  latter 
body  is  a  glucoside  of  the  formula  C21H20O9,  almost  insoluble  in  water 
and  ether,  more  soluble  in  boiling  alcohol,  chloroform  and  benzol, 
easily  soluble  in  hot  glacial  acetic  acid,  melts  at  228°-230°  and  is  de- 
composed by  alkali  and  acid  into  emodin  Ci^J1^qO^-{-1^^0j  melting 
at  254°,  and  a  sugar  C6H12O5  possibly  identical  with  rhamnodulcit 
C21H20O9 + H2O = C15H10O5  -f  C6H12O5. 
From  an  older  bark  0*04  per  cent,  frangulin  and  O'l  per  cent,  emo- 
