586  Minutes  of  the  Pharmaceutical  Meeting,  {'^^iov'^.^im.'^'^' 
Artificial  gastric  juice  when  digested  with  different  oils  shows  quite  dis- 
similar results.  With  cod  liver  oil  it  gives  a  transient  mixture,  then 
separates  into  an  emulsified  fat  layer,  and  only  becomes  clear  through 
half  its  volume.  The  oils  of  olive,  rape,  flaxseed,  ground  nut,  hemp,  poppy, 
and  benne,  when  similarly  treated,  separated  at  once,  and  castor  oil  emulsi- 
fied slightly — and  all  the  oils  gave  a  slightly  acid  reaction  after  twenty-four 
hours  and  traces  of  glycerin  were  observable  in  the  aqueous  solution.  It 
would  seem  as  the  sura  of  these  experiments  that  cod  liver  oil  differs  from 
the  other  fats  because  of  its  easy  miscibility  with  the  gastric  juice,  and  then 
the  pancreatic  secretion  can  act  on  the  finely  divided  mixture,  while  other 
fats  remain  in  large  globules  and  are  not  easily  acted  on. 
Two  preparations  have  been  proposed  to  be  substituted  for  and  improve- 
ments on  cod  liver  oil. 
Lipanin,  which  is  olive  oil  with  a  small  percentage  of  free  oleic  acid. 
Fat  peptonate,  a  mixture  of  cod  liver  oil,  or  pure  olive  oil  acted  on  by  the 
pancreatic  secretion. 
Four  other  preparations  were  made  to  compare  results  with  lipanin,  viz. : 
Olive  oil  with  5  per  cent,  of  pure  phosphoric  acid ;  olive  oil  with  5  per  cent, 
lanolin  ;  olive  oil  with  J  per  cent,  sodium  oleate  ;  and  olive  oil  with  1  per 
cent,  mucilage  of  gum  arnbic. 
Lipanin  when  treated  with  artificial  gastric  juice  mixes  fairly  at  first,  but 
separates  in  a  few  minutes  nearly  pure.  Fat  peptonate,  under  same  treat- 
ment mixes,  and  after  24  hours  still  is  free  from  oil  globules ;  olive  oil  with 
half  per  cent,  oleate  of  sodium  is  the  only  other  one  that  remains  mixed ;  the 
inference  from  all  these  experiments  is  that  pure  fluid  fats  should  be  avoided, 
and  that  natural  foods  in  which  the  fats  are  divided  should  be  the  type  of 
such  remedies. 
The  reading  of  these  extracts  elicited  remarks  from  several  present.  Mr. 
England  said  that  a  French  house  was  making  a  preparation  called 
morrhuol,  to  be  used  as  substitute  for  the  pure  oil ;  and  Dr.  Lowe  said  that 
in  the  French  hospitals  the  oil  was  given  with  the  food  in  place  of  butter. 
Mr.  Brown  said  that  he  had  lately  examined  gum  arabic  which  proved  to 
be  adulterated  with  dextrin,  and  lycopodium  that  was  mixed  with  at  least 
fifty  per  cent,  corn  starch. 
Mr.  Boring  stated  that  at  a  meeting  of  the  State  Pharmaceutical  Association 
held  in  June  1887,  Mr.  England  read  a  paper  on  a  solution  of  carmine  suit- 
able for  coloring  purposes  in  pharmaceutical  preparations ;  and  that  in  mak- 
ing a  similar  preparation  he  found  when  he  had  evaporated  it  till  a  rod 
moistened  with  hydrochloric  acid  showed  no  ammoniacal  vapor  that  the 
carmine  was  precipitated  in  globules  through  the  solution,  and  thought  that 
there  was  some  fault  in- the  process.  Several  members  said  that  the  cause 
of  this  precipitation  of  color  was  doubtless  the  destruction  of  the  com- 
bination by  removing  too  much  ammonia  and  that  more  careful  ma- 
nipulation and  a  lower  temperature  in  evaporation  would  obviate  this 
trouble. 
There  being  no  further  business,  on  motion  the  meeting  adjourned. 
T.  S.  WiEGAND,  Registrar. 
