4-2 
Digitalis  Glue o sides  and  Allied  Drugs.  { Ajan^0aurry  ^f™- 
crystals.  (Compare  also  gitalin  p.  31.)  (Schweizer  Wochen- 
schrift  fur  Chemie  und  Pharmazie  191 1,  p.  162.) 
Glucodigitalins  was  the  name  given  by  Ludwig  to  those  prepara- 
tions of  digitalis,  which  were  proved  to  have  the  characteristics 
of  glucosides,  in  contradistinction  to  acrodigitalins  (which  see). 
Archiv  der  Pharmazie,  Vol.  194,  p.  213. 
Hydrodigitoic  acid,  C26  H44  Oe,  is  formed  together  with  digitoic 
acid  by  heating  digitogenic  acid  with  solution  of  caustic  potash. 
It  softens  at  2400  C.  (Archiv  der  Pharmazie  1893,  p.  457. — 
Berichte  der  deutschen  chemischen  Gesellschaft  Berlin  1899, 
P-  339-) 
Oxydigitogenic  acid,  C28  H42  09,  is  obtained  from  digitogenin  by 
oxidation  with  potassium  permanganate  in  alkaline  solution. 
(Kiliani,    Berichte    der    deutschen    chemischen  Gesellschaft 
Berlin  1891,  p.  345,  and  1899,  p.  2205.) 
Paradigitogenin  is  formed  under  special  conditions  during  the 
hydrolysis  of  digitonin.    (Archiv  fur  experimentelle  Pathologie 
1875,  Vol.  3,  p.  25.) 
Pseudodigitoxin  is  the  name  given  by  Burmann  to  a  soluble  gluco- 
side,  similar  to  gitalin,  and  obtained  from  digitalis  leaves. 
(Schweizer  Wochenschrift  fur  Chemie  und  Pharmazie  1911, 
p.  33-) 
Substance  cristallisee  inerte  (Nativelle)  is  identical  with  digitin 
Nativelle. 
Toxigenon,  C20  H26  Os  or  C19  H24  03,  is  a  crystalline  body,  formed 
by  the  oxidation  of  digitaligenin  or  of  anhydro-digitoxigenin 
by  means  of  chromic  acid ;  it  commences  to  decompose  at 
2200  C,  without  melting.     (Kiliani,  Berichte  der  deutschen 
chemischen  Gesellschaft  Berlin  1898,  p.  2459;  :899,  p.  2199.) 
Toxiresin  is,  according  to  Schmiedeberg,  a  product  of  decomposi- 
tion of  digitoxin,  soluble  in  ether.    (Archiv  fiir  experimentelle 
Pathologie  1875,  Vol.  3,  p.  39,  and  Vol.  4,  p.  191.) 
Various  color  reactions  have  been  suggested  for  the  chemical 
identification  of  the  digitalis  glucosides ;  some  of  these  have  gained 
full  recognition  in  laboratory  work,  but  most  of  them  cannot  be 
considered  conclusive  without  the  aid  of  biological  tests.  The 
first   fairly   characteristic   reaction   was   already    discovered  by 
Homolle.17    He  found  that  his  digitalin  gave  an  intense  green 
coloration  with  concentrated  hydrochloric  acid.     To  which  con- 
17  Homolle,  Union  medicale  1872,  p.  295. 
