Ajanu°ary  1913™'}  Digitalis  Glucosides  and  Allied  Drugs.  39 
(Kiliani,  Archiv  der  Pharmazie  1899,  p.  466. — Berichte  der 
deutschen  chemischen  Gesellschaft  Berlin  1899,  p.  2205.) 
Digitoleinic  acid.  Kosmann  precipitated  an  aqueous  extract  of 
digitalis  leaves  with  lead  subacetate  and  treated  the  precipitate 
thus  produced  by  warming  with  a  solution  of  sodium  carbonate. 
By  treating  the  liquid  with  sulphuric  acid,  he  was  able  to 
precipitate  two  substances ;  of  these  one  soluble  in  ether  was 
called  by  him  digitoleinic  acid.  It  forms  a  fatty,  granular  mass. 
(Journal  de  connaissance  medicale  1845,  Vol.  13,  Buchner's 
Repertorium  fur  Pharmazie  1846,  Vol.  92,  p.  348.) 
Digitonein,  according  to  Schmiedeberg,  is  a  body  formed  by  the 
decomposition  of  digitonin  by  means  of  hydrochloric  acid ; 
it  is  insoluble  in  ether.  (Archiv  fur  experimentelle  Pathologie, 
Vol.  3,  p.  22.) 
Digitonin,  when  anhydrous,  occurs  as  an  amorphous  body,  while 
with  5H0O  it  is  a  crystalline,  chemically  uniform  body ;  its 
formula  is  C54  H92  028  or  C54  H92  0  28  +  5  H20.  (Compare 
page  30.) 
Digitonin,  amorphous,  is  digitonin  Schmiedeberg. 
Digitonin  cryst.  is  digitonin  Kiliani. 
Digitonin  Kiliani,  is  pure,  crystalline,  hydrated  digitonin  (C54H92 
028  +  5H20).  Archiv  der  Pharmazie  1893,  p.  460. — Berichte 
der  deutschen  chemischen  Gesellschaft  Berlin  1891,  p.  339 
and  3951.) 
Digitonin  Schmiedeberg  is  amorphous,  anhydrous  digitonin 
(C54H92  0  28).  According  to  Kraft,  digitonin  Schmiedeberg 
and  digitonin  Kiliani  are  not  identical ;  he  therefore  suggests 
the  designation  "  digitsaponin "  for  digitonin  Schmiedeberg. 
(Kraft,  Schweizer  Wochenschrift  fur  Chemie  und  Pharmazie 
1911,  p.  175.) 
Digitophyllin,  according  to  Kiliani,  is  a  chemically  uniform  body 
with  the  formula  C32  H52  O10.  According  to  Keller,  Arnaud 
and  Adrian,  it  is  identical  with  the  French  digitaline  cristallisee. 
But  neither  the  identity  nor  the  dissimilarity  of  these  two 
digitalis  products  has  as  yet  been  conclusively  proved.  (Archiv 
der  Pharmazie  1897,  Vol.  235,  p.  426. — van  Rijn,  The  gluco- 
sides 1900,  p.  425.) 
Digitoresin,  according  to  Schmiedeberg,  is  a  substance  soluble 
in  ether,  formed  by  treating  digitonin  with  hydrochloric  acid. 
