122 
Progress  in  Pharmacy. 
f  &.m.  Jour.  Pharm. 
\      March,  1913 
Each  of  the  four  methods  discussed — the  one  and  twelve-hour 
frog  methods,  the  guineapig,  and  cat  methods — has  certain  ad- 
vantages not  possessed  by  the  others. 
The  method  which  possesses  the  greatest  number  of  advantages 
is  the  cat  method  of  Hatcher — 
(a)  It  is  accurate  to  within  ten  per  cent. 
(b)  It  gives  constant  results  from  year  to  year. 
(c)  It  provides  a  means  of  detecting  the  presence  of  de- 
terioration. 
(d)  It  is  the  least  affected  by  adventitious  factors. 
(e)  It  tests  the  action  of  the  drug  upon  which  its  therapeutic  use 
depends. 
(f)  It  is  not  too  difficult  for  general  use. 
(g)  It  is  neither  too  time  consuming  nor  too  costly. 
(h)  By  it  widely  different  preparations  can  be  compared  ac- 
curately. 
(*)  Its  results  are  transferable  to  man. 
(/)  It  has  the  widest  range  of  applicability  of  all  the  methods. 
Neither  the  frog  nor  the  guineapig  method  fulfils  so  many  of 
the  essential  requirements  as  does  the  cat  method. 
The  cat  method  fails  in  no  single  requisite  and  has  far  fewer 
disadvantages  than  any  other  method  yet  proposed. 
PROGRESS  IN  PHARMACY. 
A  Quarterly  Review  of  Some  of  the  More  Interesting 
Literature  Relating  to  Pharmacy  and  Materia  Medica. 
By  M.  I.  Wilbert,  Washington,  D.  C. 
An  unusual  amount  of  interest  is  being  manifested  in  the  pros- 
pective legislation  on  matters  relating  to  public  health  and  not  the 
least  among  these  several  subjects  is  the  legislation  designed  to 
effect,  either  directly  or  indirectly,  the  practice  of  pharmacy.  From 
38  to  40  of  the  state  legislatures  are  now  in  session  and  in  the 
majority  of  these  bodies  some  form  of  legislation  more  or  less 
directly  affecting  the  practice  of  pharmacy  is  being  considered. 
Legislation  designed  to  further  regulate  the  manufacture  and 
sale  of  habit  forming  drugs  is  being  endorsed  by  physicians  and 
pharmacists  generally  because  of  the  general  appreciation  of  the 
