128 
Progress  in  Pharmacy. 
JAm.  Jour.  Pharm. 
I      March,  1913. 
Cresol  Preparations. — Raschig,  F.  {Siidd.  Apoth.-Ztg.,  1912, 
v.  52,  p.  670),  states  that  J.  Schenkel  was  the  first  to  discover  the 
crude  tar  distillates,  containing  approximately  33  per  cent,  of 
phenols,  could  be  made  miscible  with  water  by  the  addition  of 
rosin  soap.  Schenkel  marketed  a  preparation  of  this  kind  under 
the  name  "  Sapokarbol  II."  This  was  subsequently  imitated  by 
other  manufacturers  and  under  the  name  "  Creolin  "  or  "  sheep- 
dip  "  has  found  a  widespread  application  and  for  some  purposes  it 
is  claimed  to  be  more  efficient  than  the  corresponding  soap  solution 
of  cresol. 
Cycloform. — Is  the  name  applied  to  isobutyl  para-aminobenzoate 
or  para-aminobenzoic  acid  isobutyl  ester.  It  occurs  as  a' fine  white, 
crystalline,  odorless  powder  that  is  soluble  in  ether,  benzol,  acetone, 
alcohol  and  olive  oil  but  is  only  slightly  soluble  in  water.  It  melts 
at  65  °.  Cycloform  acts  on  wound  surfaces  and  mucous  mem- 
branes as  a  superficial  and  prolonged  anaesthetic  and  as  a  mild 
antiseptic.   (/.  Am.  Med.  Assoc.,  191 2,  v.  59,  p.  2150.) 
Digitalis  Preparations  and  Some  of  the  New  Substitutes  for 
them. — An  editorial  (/.  Am.  Med.  Assoc.,  1912,  v.  59,  pp.  2074- 
2075)  calls  attention  to  a  report  from  the  Pharmacological  Lab- 
oratories at  Cambridge,  England,  which  reiterates  the  frequently 
made  statement  that  so  far  not  one  of  the  new,  generally  proprietary, 
preparations  of  digitalis  has  made  a  successful  bid  for  superiority 
over  an  active  tincture  of  digitalis.  (See  also  Ibid.,  1913,  v.  60, 
P-  J43-) 
Digitalis. — Hatcher  and  Eggleston  (/.  Am.  M.  Assoc.,  1913, 
v.  60,  pp.  499-503)  report  a  study  of  the  relative  emetic  and 
cardiac  activities  of  the  more  commonly  used  digitalis  bodies  in 
which  they  call  attention  to  their  previously  reported  observation 
that  the  emesis  sometimes  produced  by  digitalis  bodies  is  due 
mainly,  if  not  entirely  to  the  action  on  the  vomiting  center  in  the 
medulla  and  conclude  that  we  at  present  have  no  means  of  securing 
the  cardiac  action  of  the  digitalis  bodies  without  subjecting  the 
vomiting  center  to  their  influence  at  the  same  time.  (See  also 
Ibid.,  p.  371.) 
Elarson. — A  new  arsenic  preparation  containing  strontium  and 
chlorine,  occurs  as  a  nearly  colorless  and  odorless  amorphous 
powder,  insoluble  in  water  but  slightly  soluble  in  alcohol,  ether 
and  fatty  oils.  Elarson  contains  13  per  cent,  arsenic  and  6  per  cent, 
chlorine.    (Suedd.  Apoth.  Ztg.,  1913,  v.  53,  p.  20.) 
> 
