246  Juice  of  Blueberry  as  Indicator.  {^j^riST™' 
Pig  No.  10,  Weight  309  Gm.  Injected. — 1.5  c.c.  of  dilution 
(0.15  c.c.  of  Acetic  Fluidextract) .   Result. — No  toxic  action  noted. 
Pig  No.  11,  Weight  233  Gm.  Injected. — 2  c.c.  of  dilution  (0.2 
c.c.  of  Acetic  Fluidextract).    Result. — No  toxic  action  noted. 
Pig  No.  12,  Weight  275  Gm.  Injected. — 1  c.c.  of  dilution  (0.1 
c.c.  of  Fluidextract  of  Digitalis  U.  S.  P.).  Result. — Salivation,  but 
pig  did  not  die. 
Pig  No.  13,  Weight  305  Gm.  Injected. — 1.5  c.c.  of  dilution 
(0.15  c.c.  of  Fluidextract  of  Digitalis  U.  S.  P.  made  from  leaves 
from  store).  Result. — Convulsions,  but  pig  did  not  die  till  next 
morning. 
Pig  No.  14,  Weight  325  Gm.  Injected. — 2  c.c.  of  dilution  (0.2 
c.c.  of  U.  S.  P.  Fluidextract  of  Digitalis).  Result. — Severe  con- 
vulsions.   Dead  in  30  minutes. 
It  may  be  readily  seen  from  the  results  above  that  the  acetic 
fluidextract  of  digitalis  was  markedly  inferior  in  physiological  ac- 
tivity to  the  U.  S.  P.  product  made  from  the  same  leaves. 
In  order  to  determine  if  the  acetic  fluidextract  had  any  physio- 
logical activity  Calcium  Carbonate  and  Magnesium  Carbonate  was 
shaken  with  a  portion  of  the  acetic  fluidextract  and  after  most  of 
the  effervescence  had  ceased  the  liquid  was  filtered.  1  c.c.  of  this 
filtrate  was  now  injected  into  a  guinea  pig  which  weighed  320  Gm. 
No  convulsions  were  noticed.  Even  salivation,  frequent  defecation 
and  urination  was  not  observed.  The  pig  died  after  two  days,  but 
post  mortem  examination'  did  not  show  heart  in  firm  systole  or 
blood  vessels  engorged. 
Summary  and  Conclusion. — -The  physiological  activity  of  acetic 
fluidextract  of  Digitalis  is  undoubtedly  markedly  less  than  the 
fluidextract  made  by  U.  S.  P.  method.  In  all  probability  the  gluco- 
sides  are  promptly  broken  down  by  the  acetic  acid  that  is  present. 
Laboratories  Smith,  Kline  &  French  Co.,  Philadelphia,  Pa. 
THE  JUICE  OF  THE  BLUEBERRY  AS  AN' INDICATOR. 
By  G.  N.  Watson. 
Undoubtedly  all  have  noticed  the  greenish-blue  color  that  is 
imparted  to  the  alkaline  tongue  and  lips  by  the  common  blueberry 
(Vaccinium  corymbosum)  and  its  varieties.  This  fact,  together 
with  the  fact  that  the  juice  is  turned  to  a  beautiful  rose  color  by 
