Am.  Jour.  Pharm.  \ 
March,  igig.  J 
Digitalis  Leaves. 
181 
TABLE  I. 
Digitalis  Purpurea  from  a  Flower  Garden  in  Detroit. 
Not  Dried. 
Oven  Dried. 
S™}  Dried. 
Weight. 
Dose. 
Result. 
Weight. 
Dose. 
Result. 
Weight. 
Dose. 
Result. 
22 
22 
22.5 
22.5 
23 
O.OO4 
5 
6 
7 
8 
Alive 
Dead 
16.5 
10.5 
16.5 
14 
13-5 
O.OIO 
0.012 
O.OI5 
0.020 
0.025 
Alive 
Dead 
19 
19 
19-5 
20.5 
20.5 
O.OIO 
0.012 
0.015 
0.018 
0.022 
Dead 
23-5 
25 
25 
25 
26 
O.0045 
55 
65 
75 
0.0090 
Alive 
Dead 
23 
24 
24 
24 
24 
0.008 
O.OIO 
0.012 
O.OI4 
O.Ol6 
Dead 
24 
24-5 
24-5 
If 
0.007 
0.008 
0.009 
O.OIO 
O.OII 
Alive 
Dead 
27 
27 
27o 
29-5 
30 
0.0055 
65 
75 
85 
O.OI 
Alive 
Dead 
20 
20 
21 
21 
21 
0.006 
0.007 
0.008 
O.OO9 
O.OIO 
Alive 
Dead 
22 
22.5 
23 
24 
26 
0.007 
0.008 
0.009 
O.OIO 
O.OII 
Alive 
Dead 
Alive 
27 
29-5 
29-  5 
30-  5 
33 
0.0070 
75 
75 
So 
80 
Alive 
Dead 
24-  5 
25 
25-  5 
25  5 
25-5 
0.008 
0.009 
O.OIO 
O.OII 
0.012 
Alive 
Dead 
Alive 
Dead 
25-5 
25-5 
26 
26 
26 
0.008 
0.009 
O.OIO 
0.011 
0.012 
Dead 
<  1 
0.007  killed  none  of  3 
0.0075  killed  1  of  4 
0.008  killed  3       of  3 
Activity    153 
H.  T.  U  : .    9  + 
M.  L.  D  0.008 
Activity  in  terms  of 
Summarizing  the  above. 
0.008  killed  1  of  3 
0.009  killed  1  of  2 
0.010  killed  2  of  4 
0.011  killed  1  of  1 
0.012  killed  3  of  3 
100 
6 
O.OII 
undried  drug 
IOO^c 
72 
0.008  killed  1  of  3 
0.009  killed  3  of  3 
0.010  killed  4  of  4 
0.011  killed  2  of  3 
0.012  killed  2  of  2 
133 
8 
0.009 
81 
to  make  the  experiment  conclusive.  Such  experiments  should  be 
continued  over  a  period  not  less  than  three  years. 
In  further  consideration  of  the  previously  mentioned  criticism 
against  the  Oregon  air-dried  leaves  it  should  be  noted  that  the 
method  of  testing  was  also  called  in  question.  On  this  point,  while 
there  is  wide  divergence  of  opinion  as  to  which  of  several  methods 
shows  the  real  value  of  the  drug,  there  is  quite  general  agreement 
on  the  frog  as  the  test  animal,  and  until  clinical  evidence  is  brought 
