Am.  Jour.  Pharm.  j 
October,  19 19.  J 
Antiscorbutics.. 
671 
washing  the  mercury  in  a  second  separatory  funnel  with  at  least 
two  50  Cc.  portions  of  water.  Pass  the  several  aqueous  solutions 
quantitatively  through  a  small  filter,  collecting  the  clear  filtrate  in 
a  suitable  beaker.  Precipitate  with  silver  nitrate  after  the  addition 
of  about  5  Cc.  of  nitric  caid,  and  proceed  in  the  usual  gravimetric 
way,  employing,  if  available,  a  Gooch  crucible  in  the  operation  of 
filtering.  The  weight  of  the  silver  bromide  multiplied  by  the  factor 
1.23  will  give  the  quantity  of  monobromated  camphor  originally 
present  in  the  sample  taken  for  analysis.  A  control  should  be  run 
on  the  amalgam  in  order  to  determine  whether  any  correction  is 
necessary  for  the  presence  of  halogen  in  material  quantity. 
Summary. 
This  method  for  the  estimation  of  monobromated  camphor  in 
migraine  tablets  takes  advantage  of  the  fact  that,  when  an  aqueous- 
alcoholic  solution  of  the  camphor  derivative,  either  alone  or  in  ad- 
mixture with  other  substances,  is  subjected  to  the  action  of  sodium 
amalgam  on  heating,  among  other  changes  the  bromine  is  split  off 
quantitatively  in  the  form  of  its  sodium  salt,  which  may  then  be 
determined  gravimetrically  in  the  usual  way. 
Synthetic  Products  Laboratory, 
Bureau  of  Chemistry,  Department  of  Agriculture, 
Washington,  D.  C. 
ANTISCORBUTICS.  II.1 
In  a  previous  issue  of  The  Journal,2  reference  was  made  to 
some  of  the  experiences  which  have  led  to  the  development  of 
diverse  sorts  of  antiscorbutic  products  available  for  the  purposes  of 
infant  nutrition.  It  is  not  necessary  to  refer  back  to  the  older  expe- 
ditions in  search  of  the  North  Pole  or  to  the  experiences  of  our 
Civil  War  to  learn  how  essential  antiscorbutic  foods  may  be  to  an 
adult  as  well  as  to  the  growing  infant.  The  changes  in  our  food 
supplies  have  altered  the  dietary  habits  of  mankind,3  and,  although 
in  normal  peace  times  the  tendency  toward  a  liberal  supply  of  varied 
1  From  The  Jour,  of  Amcr.  Med.  Asso.,  August  2,  1919. 
2  Antiscorbutics,"  I,  editorial,  J.  A.  M.  A.,  73:  271  (July  26),  iqiq. 
3  Mendel,  L.  B.,  "  Changes  in  the  Food  Supply  and  Their  Relation  to 
Nutrition,"  Yale  University  Press,  1916. 
