6qo  Western  Australian  Sandalwood  Oil.  { Am.  jour.  Pharm. 
October,  19 19. 
supports  Roger's  view  that  these  salts  act  in  some  way  on  the  coat- 
ing of  the  acid-fast  bacilli.  He  is  satisfied  that  sodium  morrhuate 
is  harmless. 
The  usual  initial  dose  is  0.5  Cc.  of  the  3  per  cent,  solution,  in- 
creased by  2  to  4  minims  at  each  injection,  which  may  be  given  two  or 
three  times  a  week  until  any  reaction  occurs ;  then  a  week's  interval 
is  left,  and  the  dose  reduced.  Injections  are  given  subcutaneously 
until  they  reach  an  inconvenient  size,  such  as  2  Cc,  when  intra- 
venous injections  can  be  begun  with  0.5  Cc.  gradually  increased  in 
the  same  way. 
Clinical  trials  of  sodium  morrhuate  in  phthisical  cases  have  been 
made  by  E.  Muir  and  others,  and  the  results  are  distinctly  en- 
couraging. Rogers,  in  summing  up  these  results,  says  that  he  is 
convinced  of  its  harmlessness,  which  is  more  than  can  be  said  of 
tuberculin.  "  At  the  same  time,'''  he  adds,  "  the  fact  that  sodium 
morrhuate  causes  febrile  and  local  reactions  necessitates  great  cau- 
tion in  pushing  the  drug  beyond  the  limits  which  have  so  far  proved 
safe,  and  a  warning  is  required  regarding  the  possibility  of  harm 
being  done  by  its  injudicious  use.  With  this  caution  I  feel  that  the 
results  already  obtained  justify  me  in  bringing  sodium  morrhuate 
to  the  notice  of  the  medical  profession,  to  allow  of  the  prolonged 
trials  by  many  skilled  workers,  which  will  be  necessary  before  its 
permanent  value,  if  any,  can  be  decided,  and  the  indications  and 
contraindications  for  its  use  worked  out." 
WESTERN  AUSTRALIAN  SANDALWOOD  OIL.1 
The  January-March,  1919,  issue  of  the  Bulletin  of  the  Imperial 
Institute  contains  an  interesting  article  on  the  sandalwood  of  West- 
ern Australia,  by  Mr.  C.  E.  Lane-Poole,  conservator  of  forests  in 
Western  Australia,  in  which  he  criticizes  a  previous  note  in  the  Bul- 
letin (January-March,  vol.  XV.,  No.  1)  dealing  with  the  production 
of  sandalwood  oil  in  Mysore,  and  in  which  reference  is  made  to 
western  Australian  sandalwood,  which  Mr.  Lane-Poole  asserts 
hardly  does  justice  to  that  product.  The  Bulletin  stated  that  "so- 
called  sandalwood  exported  from  Australia  "  is  mainly  derived  from 
Fusanus  spicatus,  but  Mr.  Lane-Poole  cites  botanical  authorities 
such  as  Baron  von  Mueller,  Dr.  F.  L.  Stoward,  and  De  Candolle, 
1  Reprinted  from  The  Chemist  and  Druggist,  September  6,  1919. 
