46 PATENT FOR PURIFIED QUINOIDINE, ETC. 
it is desirable to dissolve the purified chinoidine in alcohol 
before mixing with the acids. These saline compounds I pre- 
pare for sale, either in solution or by evaporating them to 
the|olid state, and reduce them when they will allow of it, 
to powder. In all cases, the preparation should be kept in 
well closed bottles. 
The preparation of Amorphous Quinine. — I take three 
pounds of chinoidine as before, or in the purified state as 
above described (for this purpose it is best to use it before 
it is fully dried) and mix it well with twice its weight of 
pure sand, and digest in nine parts of ether (commonly 
known as sulphuric ether.) The specific gravity of the 
ether I believe most suitable, being about 735 ; I stir up 
the mixture three or four times during the digestion, which 
should continue twelve hours, and pour off the solution. 
To the residue I add nine pints of fresh ether, and proceed 
as before; I mix the two solutions, and allow them to settle; 
when perfectly bright, I pour off the fluid from the sediment 
into a retort or suitable vessel, and distil off the ether by 
means of a water-bath. The substance left in the vessel is 
to be dried in the same manner as is directed for the purified 
chinoidine. To this residue I apply the term Amorphous 
Quinine. The saline compounds are prepared by taking 
one equivalent of an acid in solution, and dissolving in it 
an equivalent of the amorphous quinine, considering car- 
bon 6, oxygen 8, hydrogen 1. I take one hundred and 
sixty-two parts of amorphous quinine to each equivalent of 
acid, all which is understood by chemists, and I form basic 
neutral or acid salts, in the usual way. 
Basic extract of Bark. — The residue left upon treating 
chinoidine with ether, in order to extract the amorphous 
quinine, contains also valuable medicinal matter. I take 
any given amount of this product, and calculating the 
amount of dry substance it contains, treat it with six times 
its weightof alcohol, generally preferring it 56° over-proof. 
I decant the clear fluid, and evaporate it to dryness, in the 
same manner as with amorphous quinine. To this product 
