250 
Analysis  of  Fluid  Extracts, 
Am.  Jour.  Pharm. 
June,  1876. 
est  (Scheffer  and  Diehl)  -612  per  cent.,  their  proportion  is  nearly  as  2  :  5, 
Mr.  Wells  has  estimated  the  amount  of  ammonium  from  which  the 
ammonium  sulphate  in  the  two  samples  proves  to  be  5*44  and  5*52 
per  cent.,  representing  respectively  3*40  and  3*45  of  the  sulphuric  acid, 
which,  deducted  from  the  assayed  amounts  of  the  latter,  leave  3*116 
and  1*566  per  cent,  of  SOs  in  combination  with  alkaloids.  Allowing 
this  to  be  combined  with  cinchonia,  we  find  the  following  percentage 
of  cinchonia  sulphate  (which  contains  io*66  per  cent.  SOs)  in  Wells' 
old  sample  14*69,  and  in  his  new  sample  29*23  per  cent.,  or,  within  a 
slight  fraction,  double  the  amount.  The  amount  of  alkaloidal  sul- 
phate, approximately  estimated  by  Scheffer  and  Diehl  by  treatment 
with  cold  water,  varied  in  four  samples  between  1 1  '75  and  22  per  cent.  ; 
a  variation  nearly  as  great  as  found  by  Mr.  Wells. 
If  the  figures,  as  obtained  by  the  different  analysts,  are  averaged  for 
the  various  compounds  actually  contained  in  cincho  quinine,  and  the 
ammonium  sulphate  be  entirely  omitted,  a  preparation  closely  resembling 
the  average  composition  of  the  article  in  question,  may  be  obtained  by 
intimately  mixing 
Quinia,  alkaloid,  5  grains,     or      Quinia  sulphate,  7*5  grains 
Quinidia,  alkaloid,  15  grains,  Quinidia  sulphate,  20*  grains 
Cinchonidia,  alkaloid,        10  grains,  Cinchonidia  sulphate,         12.5  grains 
Cinchonia,  alkaloid,         770  grains,  Cinchonia  sulphate,  180'  grains 
Cinchonia  sulphate,  ■        200  grains,  Cinchonia,  alkaloid,         780*  grains 
1,000  grs.  1,000  grs. 
Those  who  desire  a  still  closer  representation,  may  incorporate  with 
either  of  the  above  mixtures  54  grains  of  ammonium  sulphate,  which 
will  not  enhance  the  cost,  but  increase  the  weight  of  this,  as  some 
medical  journals  tell  us,  valuable  nostrum. 
COMPARATIVE  ANALYSIS  OF  CERTAIN  FLUID  EXTRACTS  BY 
IODO-HYDRARGYR ATE  OF  POTASSIUM. 
BY  HENRY  C  SCHRANCK,  PH.G. 
(Fr-om  an  Inaugural  Essay,  presented  to  the  Nenv  York  College  of  Pharmacy.) 
The  writer  of  this  essay  selected  the  fluid  extracts  of  nux  vomica, 
stramonium,  belladonna,  conium,  hyoscyamus  and  veratrum  viride  as 
those  most  suitable  for  his  purposes,  and  in  each  case  obtained  original 
packages  from  the  several  manufacturers  for  the  purposes  of  examina- 
tion. 
