Am.  Jour.  Pfearm.) 
July,  1876.  J 
Hydrobr ornate  of  Quinia. 
middle  of  the  cone  by  a  grain  of  gold  and  a  little  borax.  I  cut  off 
the  point  of  the  cone  to  create  a  small  opening  there,  as  I  also  per- 
forate the  sides  of  the  cone  near  its  apex  with  a  pin. 
Before  leaving  this  subject,  I  will  mention,  with  a  few  words,  a 
most  simple  device  which  I  have  frequently  used  to  promote  filtration, 
and  which  consists  of  a  piece  of  rubber  or  glass  tubing,  about  1  foot 
long,  fastened  into  the  tube  of  the  funnel  when  the  arrangement  is 
ready  for  use.  The  internal  diameter  of  this  tube  should  be,  at  the 
most,  of  an  inch.  A  tube  similar  in  shape  to  Weil's  filtering  tube, 
but  of  different  dimensions,  looks  more  elegant  and  meets  the  objec- 
tion against  bringing  the  filtered  liquid  in  contact  with  India  rubber. 
The  upper  wider  part  is  3  inches  long,  the  lower  narrow  part  is  made 
of  a  barometer  tube,  and  of  the  length  first  named.  This  little 
device  meets  moderate  expectations  very^well,  and  will  often  be  found 
a  good  help. 
For  washing  out  precipitates,  on  a  larger  scale,  I  use  large  funnels, 
half  filled  with  coarse  glass  powder  (glass  heated  to  redness,  thrown 
into  cold  water,  powdered  and  the  finest  powder  sifted  off),  on  the 
evened  surface  of  which  is  placed  a  round  piece  of  filtering  paper,  in 
close  contact  with  the  sides  of  the  funnel,  for  the  reception  of  the 
precipitate.  As  a  receptacle,  I  use  a  Woolf's  bottle  of  proper  size  ; 
the  filtering  pump  has  an  evacuation-tube  of  12  feet  length. 
SOLUTION  OF  HYDROBROMATE  OF  QUINIA  FOR  HYPODERMIC 
INJECTION. 
BY  WILLIAM  SILVER  THOMPSON. 
The  commercial  "  bromide  of  quinia  "  is  not  sufficiently  soluble 
to  make  a  concentrated  solution  for  hypodermic  use  ;  and  having  been 
requested  by  Prof.  William  T.  Howard,  to  prepare  such  a  solution, 
containing  four  grains  in  twenty  minims,  or  ninety-six  grains  in  each 
fluidounce,  I,  at  first,  availed  myself  of  the  reaction  between  quinia 
sulphate  and  calcium  bromide,  but  not  being  satisfied  with  the  process, 
I  devised  the  following,  which  has  since  been  used  with  success,  and 
gives  a  satisfactory  result  : 
Take  of  Quinia  sulphate,  .        96  grains. 
Distilled  water, 
Diluted  sulphuric  acid, 
Water  of  ammonia,  and 
Hydrobromic  acid,  of  each  a  sufficient  quantity. 
