Amsep?r;i876arm'}  Contributions  from  Ihe  School  of  Pharmacy,  etc,  391 
or  but  slightly.  Taking  a  final  precipitate  by  caustic  soda,  the  alkaloids 
were  then  approximately  separated  from  each  other  by  use  of  ether  as 
a  solvent,  potassium  iodide  to  precipitate  quinidia,  potassium  sodium 
tartrate  to  precipitate  cinchonidia,  etc.1 
1.  "  Ayer's  Ague-Cure."  Each  bottle  contains  six  fluidounces  of 
a  dark  red  syrupy  liquid,  with  a  very  slight  white  sediment.  Taste, 
very  bitter  and  slightly  peppery,  with  a  slight  taste  and  odor  of  winter- 
green  oil.  An  alcoholic  extract  (tincture)  of  cinchona  bark,  with  ad- 
ditional and  amorphous  cinchona  alkaloids  (chinoidin),  heavily  saccha- 
rine and  slightly  aromatized.  It  contains  a  resin  which  presented  the 
physical  properties  and  gave  apparently  the  physiological  effects  of 
podophyllum  resin,  but  it  was  not  so  far  separated  from  cinchona  con- 
stituents as  to  be  positively  determined.  It  has  free  and  combined  sul- 
phuric acid  and  the  white  sediment  is  calcium  sulphate  (from  the  cal- 
cium salts  of  the  bark).    In  one  fluidounce  : 
Amorphous  alkaloids  (Chinoidin),         .  3*2  grains. 
Cinchonia,       ....  3*0  " 
Cinchonidia,         ....  0*7  " 
Quinia,  ....  o*8  " 
Quinidia,  .  .  .  i*o  " 
Total,  ...  87  " 
The  cost  of  a  bottle  will  not  exceed  35  cents — the  price  being  at 
wholesale,  65  cents,  and  at  retail  $1. 
2.  "  Wilhoft's  Antiperiodic  Fever  and  Ague  Cure."  The  bottle 
contains  four  fluidounces  of  a  thin,  dark-red  liquid,  with  the  odor  of 
cinchona  bark,  a  very  bitter  and  acid  taste,  and  acid  reaction.  It  con- 
sists essentially  of  an  infusion  of  cinchona  bark  made  with  water  con- 
taining aromatic  sulphuric  acid  (like  those  of  the  U.  S.  P.),  and  probably 
with  an  addition  of  quinia  sulphate.  One  fluidounce  contains  3*0  grains 
of  quinia  and  5*4  grains  of  free  and  combined  sulphuric  acid  (1*5  grains 
free).  Cost  of  a  bottle,  not  over  25  cents  ;  price,  $9  per  dozen,  $1.50 
per  bottle. 
3.  "  Christie's  Ague  Mixture."  A  bottle  contains  seven  fluid- 
ounces  of  a  very  dark,  syrupy  liquid  one-fourth  filled  with  sediment, 
and  having  a  very  bitter  and  peppery  taste  and  an  odor  of  common 
molasses.    The  sediment  was  powdered  capsicum  and  a  little  resinous 
Fliickiger  &  Hanburys  Pharmacographia,  327. 
