68 
ON VALERIANATE OF QUININE. 
posed by sulphuretted hydrogen, afforded a liquor from 
which I extracted pure crystallized succinic acid. The ana- 
lysis gave — 
Found. Calculated. 
I. II. 
Carbon - - - 40.27 40.4 40.67 
Hydrogen - - 5.28 5.1 5.08 
Oxygen - - 54.45 54.5 54.25 
To explain the tranformation of the asparagine into 
succinate of ammonia, we may suppose the pre-existence 
of succinic acid in the asparagine and its production by a 
disintegration induced by the fermentation. But this view 
of the subject seems improbable to me. I rather think 
that the crystallized asparagine, the formula of which only 
differs from that of succinate of ammonia by 2 equiv. of hy- 
drogen, takes this hydrogen from the putrefying matters by 
virtue of an action analogous to the tranformation of blue 
indigo into white indigo, under the reducing influence of 
the organic matters undergoing putrefaction. 
I hope however to resolve this questiou by direct experi- 
ment. — Ibid, from Comptes Rendus 
ART. XVIII.— VALERIANATE OF QUININE— ITS THERAPEUTIC 
EMPLOYMENT— MODE OF PREPARATION AND ADMINIS- 
TRATION. 
(Translated from the French — VAbeille Medicate) 
Dr. Francis Devay, Physician to the Hotel Dieu de Lyon, 
through an essay published in the Gazette Medicate, directs 
the attention of practitioners to a new combination of valerianic 
acid with a vegetable alkali — quinine. We are induced to 
augur favorably of this union of the active principle of vale- 
