ON VALERIANATE OF QUININE. 
71 
double decomposition, in mixing sulphate of quinine with va- 
lerianate of lime or baryta, both being dissolved in weak 
alcohol. We have ourselves obtained this salt in mixing an 
alcoholic solution of the neutral sulphate of quinine with an 
alcoholic solution of valerianate of potash. 
The process succeeds, after several successive trials, to 
insure the perfect decomposition of the two salts. These me- 
thods are only good in saving time ; it is far better to act in a 
direct manner, so as to have finer and purer products. 
Whatever mode of preparation be adopted, it should 
always be borne in mind that the solution must be evaporated 
slowly, with a gentle heat, and the crystals not to be sepa- 
rated from the mother waters except to dry them in the open 
air. 
Valerianate of quinine may be distinguished as follows: — 
1st. A concentrated alcoholic solution of valerianate of 
quinine precipitates the concentrated neutral aqueous solution 
of nitrate of silver : this precipitate is redissolved in a large 
quantity of water. 
2d. An aqueous solution of valerianate of quinine does not 
precipitate one of chloride of barium. 
3d. This aqueous solution, submitted to ebullition, allows 
some oleaginous drops of melted hydrated valerianate to 
separate. 
4th. If this solution be treated with acids, valerianic acid 
is disengaged, which may easily be recognized by its odour ; 
and if this decomposition be effected with crystallized vale- 
rianate of quinine and a concentrated liquid acid, valerianic 
acid will be obtained in an oleaginous form. 
Mode of Administration. 
Like the valerianate of zinc, this of quinine being very 
delicate, or more correctly speaking, easily decomposed, it is 
best to administer it in the most simple form : in this belongs 
a necessary condition to its successful use. 
We mostly give it in a gummous solution. Five deci- 
