72 
ON VALERIANATE OF QUININE. 
grammes of the salt, (8 grs.) according to our experiments 
with Mr. Guillermond, dissolve easily in 100 grammes of 
gummous vehicle. One of the great advantages of valerianate 
of quinine is to be able to dissolve it easily in oil, and use it 
in this manner for frictions and embrocations upon the region 
of the spleen. With this object we have made use of the 
following liniment : 
Jfe Olive oil, 60 grammes. 
Valerianate of quinine, 1 gramme. 
For neuralgia we use commonly pills containing 6 centi- 
grammes each, prescribed in the simplest manner. 
To appreciate the therapeutic value of valerianate of qui- 
nine, Mr. Devay reports, out of many cases under his obser- 
vation, 14, for the most part severe and complicated intermit- 
tent fevers, which were cured by the administration of vale- 
rianate of quinine, when the sulphate even proved abortive. 
Each dose was from 10 to 40 centigrammes (1£ to 6 grs.) a day, 
according to circumstances. The author cites no instances of 
failure, and mentions no inconvenience resulting from the em- 
ployment of this new therapeutic agent. 
He concludes thus : 
1st. Valerianate of quinine is a superior antiperiodic to the 
sulphate by its nevro-sthenic properties, and because it acts in 
smaller doses. 
2d. Its pure and simple administration is of equal value 
with that of cinchona and the nevritiques combined. 
3d. In fevers of the worst character ( ataxiques-malignes) it 
is sought to render the most eminent services by its specific 
properties. A. D. 
