228     INFLUENCE  OF  LIQUOR  POTASSiE  ON  HENBANE,  ETC. 
OSBORNE'S  SYRUP. 
[The  following  formula  for  Osborne's  Syrup  has  been  sent  to  us  by  R. 
B.  Saunders,  of  Chapel  Hill,  N.  C,  who  says :  "  I  think  it  is  one  of  the 
most  valuable  preparations  that  can  be  made  for  children ;  nothing  can 
excel  it.  It  is  also  very  useful  for  diseases  of  the  bowels  in  summer. 
Large  quantities  of  it  are  used  in  this  part  of  the  State. — Ed.  Am.  Journ. 
Pharm.] 
P  Rad.  Rhei  Cont.  3xiJ. 
Sem.  Anisi  3xiJ. 
Rad.  Glycyrrh.  5xi?« 
Aquse  Bullienti  Ix^v- 
Mannse  jJij-H. 
Tr.  Opii  Camp.  lij-^. 
Sal.  Tartari  grs.  225 
Simmer  the  first  four  articles  over  a  slow  fire  till  reduced  to 
two-thirds  ;  then  add  the  manna  and  strain.  Make  a  syrup  with 
4f  lbs.  (Troy)  white  sugar;  then  add  the  paregoric  and  saL 
tartar,  and,  in  warm  weather,  a  wine  glass  of  French  brandy. 
ON  THE  INFLUENCE  WHICH  LIQUOR  POTASSIE  AND  OTHER 
ALKALIES  EXERT  UPON  THE  PREPARATIONS  OF 
HENBANE,  STRAMONIUM,  AND  BELLADONA. 
By  A.  B.  Garrod,  M.  D. 
Physician  to  University  College  Hospital. 
Delivered  before  the  Royal  Medical  and  Chirurgical  Society,  Tuesday,  November 
24:th,  1857,  Sir  Charles  Locock,  Bart.,  President,  in  the  Chair. 
The  author  first  alluded  to  the  frequent  exhibition  of  henbane 
with  liquor  potassse,  and  brought  forward  many  proofs  that  such 
combinations  were  often  administered.  He  also  stated  that  the 
like  mixtures  were  recommended  by  both  medical  and  surgical 
authors.  Dr.  Garrod  then  proceeded  to  detail  experiments  which 
demonstrated  beyond  doubt  that  the  active  principle  of  henbane 
was  destroyed  by  liquor  potassse  and  other  caustic  alkalies  ;  and 
that  such  a  combination  was  inert,  both  when  topically  applied 
(as  evidenced  by  the  absence  of  power  in  causing  dilatation  of 
the  pupil  of  the  eye),  and  also  when  internally  administered. 
Similar  observations  were  next  detailed  upon  the  preparations 
of  stramonium  and  belladonna,  and  the  results  were  found  to  be 
