m.  Jour.  Pharm.\ 
August,  1895.  J 
Vib urn u m  Prn n ifo liu m . 
393 
bitter  taste.  The  extractives  were  then  allowed  to  evaporate  down 
and  their  solubility  in  water  was  taken.  Of  the  Viburnum  opulus 
O  OO459  gramme  was  dissolved,  and  of  the  Viburnum  prunifolium 
0.005  gramme,  showing  both  to  contain  about  the  same  amount  of 
the  principles  soluble  in  water.  This  extractive  was  of  a  clear, 
greenish  color  and  very  bitter,  that  of  the  opulus  being  the  more 
bitter  of  the  two. 
The  residues  remaining  after  treating  the  chloroformic  extracts 
with  water  were  next  treated  with  a  small  quantity  of  petroleum 
spirit  and  filtered,  the  total  extractive  of  the  Viburnum  opulus 
being  0-0834  gramme,  and  that  of  the  V.  prunifolium  0-391 5  gramme. 
These  figures  show  a  marked  difference  in  the  amounts  of  the  fixed 
oil  (?)  contained  in  the  two  barks.  The  physical  properties  of  this 
fatty  material  from  the  different  barks  were  similar  in  most  respects. 
Both  were  of  a  pale  green  to  yellow  color,  rather  sticky,  showing 
the  presence  of  a  small  quantity  of  resinous  matter ;  hard  to 
saponify,  darkened  with  sulphuric  acid,  and,  in  case  of  the  opulus,  a 
slight  reaction  was  obtained  with  hydrochloric  acid. 
The  chloroformic  residues  which  remained,  after  extracting  with 
water  and  petroleum  spirit,  were  macerated  for  two  days  in  80  per 
cent,  alcohol.  The  quantity  of  extractives  obtained  thereby  was,  of 
Viburnum  opulus,  0-122  gramme,  and  of  the  V.  prunifolium,  00375 
gramme,  showing  the  extractive  of  the  opulus  to  be  considerably 
larger  than  that  of  the  prunifolium.  The  physical  characteristics 
were  similar.  Evaporated  to  small  bulk  and  poured  into  acidulated 
water  gave  a  large  precipitate  of  resin  from  the  solution  of  Viburnum 
opulus,  but  scarcely  any  with  the  prunifolium. 
The  powdered  drugs  which  had  been  treated  with  chloroform 
were  dried  and  subjected  to  the  action  of  alcohol  for  fourteen  hours. 
The.  quantity  of  extractive  from  each  was  as  follows  :  Viburnum 
opulus,  1-515  gramme,  and  V.  prunifolium,  0969.  The  only  distin- 
guishable point  of  difference  in  these  extracts  was  the  very  astringent 
taste  in  that  of  the  opulus,  which  was  almost  entirely  lacking  in  the 
extractive  of  the  prunifolium.  Evaporating  to  small  bulk,  and  pour- 
ing into  a  large  volume  of  water,  a  precipitate  of  resin  came  down 
from  both  solutions,  but  much  larger  from  the  prunifolium  than  from 
the  opulus. 
The  analysis  was  continued  through  an  alcoholic  and  aqueous 
solution  of  the  dregs  in  turn,  and  an  examination  was  also  made  of 
