5'S 
Abstracts  from  Theses. 
(  A.m.  Jour.  Pharm. 
I     October,  1895. 
ABSTRACTS  FROM  THESES. 
Contribution  from  the  Chemical  Laboratory  of  the  Philadelphia  College  of 
Pharmacy.    No.  147. 
KOLA. 
Nathan  L.  Thompson,  Ph.G.,  estimated  the  total  alkaloids  and  the 
tannin  of  some  specimens  of  this  drug  which  he  obtained  in  com- 
merce. He  applied  three  methods  for  extracting  the  alkaloids. 
In  the  first,  these  principles  were  extracted  from  the  powdered  or 
finely  chopped  nuts  by  maceration  with  chloroform,  purified  by 
treatment  with  acidulated  water  and  removed  from  the  liquid, 
which  was  filtered  from  the  greenish-yellow  fatty  substance  that 
separated,  by  rendering  it  alkaline  with  sodium  hydrate  and 
agitating  it  with  chloroform.  The  second  method  consisted  in 
exhausting  the  drug  with  2  per  cent,  hydrochloric  acid,  and,  after 
making  alkaline  with  sodium  hydrate,  removing  the  alkaloids  with 
chloroform.  Lloyd's  process  with  ferric  hydrate  was  employed 
as  the  third  means  of  estimation.    The  crvstals  of  the  alkaloids 
Specimen. 
Condition. 
Moisture. 
Ash. 
Tannin  in 
Original  Absolutely 
Drug.        Dry  Drug. 
Dry 
7'55 
3-19 
173 
187 
6'95 
2"20 
173 
i-86 
3  
Fresh 
56-65 
3-66 
1-24 
2-85 
4  
Partly  dried 
3800 
3'66 
1-52 
2-47 
TOTAI,  ALKALOIDS. 
Means  of  Extraction. 
Specimen. 
Original  Drug. 
Absolutely  Dry  Drug. 
1 
2 
3 
4 
1 
2 
3 
4 
1  -co 
•55 
•80 
75 
ro8 
•59 
1-84 
I '22 
Acidulated  water  .  .  . 
i-35 
75 
•85 
I'OO 
1-46 
•80 
1  '96 
1-62 
Lloyd's  process  .... 
i'35 
75 
1-46 
173 
