532 
Note  on  Sinalbin  Mustard  Oil. 
f  Am.  Jour.  Pharm. 
I     October.  1895. 
first  two  days  to  the  extreme  heat  of  the  midday  sun  ;  it  is  better 
to  take  it  in  about  nine  o'clock,  and  then  put  it  out  again  between 
three  and  four  o'clock.  Those  who  use  the  evaporators  are  warned 
against  an  excessively  high  temperature. 
Great  care  must  be  taken  when  removing  the  pods  from  the  trees 
that  they  be  cut  off  with  a  good,  sharp  knife,  not  pulled  off.  If 
pulled  off,  the  little  knob  at  the  base  of  the  stem  of  the  pod  is 
injured,  and  the  tree  will  not  bear  from  the  same  spot  the  following 
year.  If  the  pods  are  cut  off  carefully,  the  tree  goes  on  bearing 
from  the  same  spot  year  after  year. 
NOTE  ON  SINALBIN  MUSTARD  OIL. — 
By  L.  E.  Sayre. 
Since  writing  the  article  on  "  A  Review  of  the  Constituents  of 
White  and  Black  Mustard  Seed,"  published  in  the  July  number  of 
this  Journal,  Prof.  J.  U.  Lloyd  has  called  my  attention  to  an  article 
by  H.  Salkowski,  in  Berichte  d.  dentsch.  chem.  Ges.,  1889,  v°l-  22,  p. 
2137,  in  which  it  is  stated  that  the  acid  which  Will  and  Lauben- 
heimer  obtained  from  sinalbin,  and  pronounced  to  be  the  ortho 
oxyphenylacetic  acid,  has  none  of  the  properties  of  either  ortho  or 
meta  oxyphenylacetic  acid,  but  seems  to  be  identical  with  the  para- 
acid.  H.  Salkowski  manufactured  the  sinalbin  mustard  oil  by  treat- 
ing para-oxybenzylamin  with  CS2,  and  the  resulting  product  with 
HgCl2.  The  sinalbin  mustard  oil  thus  obtained  has  a  burning  taste, 
and  produces  blisters  on  the  skin ;  is  soluble  in  dilute  alkali,  but 
insoluble  in  water.    It  only  slightly  volatilizes  with  steam. 
This  being  the  case,  I  desire  to  change  the  possible  reactions  lead- 
ing to  a  synthetized  preparation,  as  published  in  the  article  referred 
to,  as  follows : 
(1)  Beginning  with  the  para-nitro-toluidene 
/CH3(i) 
XN02(4) 
add  bromine  and  heat  to  1300  to  1600  in  a  sealed  tube  until  the 
reaction  is  completed.    The  result  will  be  para-nitro-benzyl  bromide 
,CHJBr(i)  . 
C.H  / 
XN02  (4) 
Treat  this  with  a  reducing  agent  (Zn  -f  HC1).  The  result  will  be 
ortho-amido-benzyl  bromide,  etc.    See  Amer.  Jour.  Pharm.¥  July,  p. 
345- 
