lOQ 
PraGtical  Notes. 
(  Am.  Jour  Pharm  _ 
1       Feb.,  1883. 
tions  for  its  preparation :  Rub  the  requisite  quantity  of  castor  oil 
necessary  for  making  flexible  collodion,  with  a  little  zinc-white,  add 
the  collodion,  and  dip  glass  plates  into  the  mixture,  repeating  this 
twice  or  three  times  until  the  film  of  collodion  is  of  the  desired  thick- 
ness ;  then  spread  upon  it  a  concentrated  solution  of  isinglass,  and 
when  dry,  remove  from  the  glass  plate. — Rundschau,  1882,  p.  662. 
Preparation  of  Tannate  of  Quinine. — Julius  Fiebert  recommends  the 
following  process  for  obtaining  this  compound  tasteless:  Dissolve  20 
parts  of  sulphate  of  quinine  in  80  parts  of  water  with  the  aid  of  suffi- 
cient dilute  sulphuric  acid,  dilute  with  sufficient  water  to  obtain  about 
1000  parts  of  solution,  and  add  thereto  a  solution  of  sodium  carbonate 
40  parts  in  water  160  parts.  Collect  the  precipitated  hydrate  of 
quinine  in  a  filter,  wash  well  with  cold  distilled  water,  drain,  and 
while  still  moist,  dissolve  in  200  parts  of  96  per  cent,  alcohol,  filter,, 
and  drop  the  filtrate,  with  continued  agitation,  into  a  clear  solution 
of  60  parts  of  tannin  in  1000  parts  of  cold  distilled  water;  set  aside 
for  several  hours,  collect  the  nearly  white  precipitate  upon  a  moist  filter^ 
wash  with  distilled  water  of  30°C.,  until  the  filtrate  has  no  longer  any 
astringent  taste,  drain,  dry  upon  bibulous  paper  at  a  moderate  temper- 
ature, and  rub  to  powder.  The  yield  is  between  60  and  65  parts. — 
Zeitschr.  Oester.  Apoth.  Ver.,  1882,  p.  4ol. 
Kairine  is  an  alkaloid,  which  has  been  prepared  synthetically  by 
Professor  Dr.  Otto  Fischer.  Experiments  have  shown,  that  only  such 
hydrated  chinoline  derivatives  are  free  from  local  action,  and  at  the 
same  time  are  capable  of  lowering  the  febrile  temperature,  the  nitro- 
gen, of  which,  besides  its  union  with  two  atoms  of  carbon  in  the  chin- 
oline ring,  is  united  with  the  carbon  of  a  methyl  group,  or  of  another 
alcohol  radical.  Such  action  was  observed  from  the  hydruret  of  oxy- 
chinoline-methyl,  having  the  formula  C^oHjgNO,  and  which  has  been 
called  kairine. 
For  obtaining  it,  oxychinoline  is  first  prepared  by  C.  Bedall  and 
O.  Fischer  ("  Berichte,  1881,  p.  442  and  1366)  from  Lubavin's  (1869) 
chinolinesulphonic  acid,  by  melting  it  with  caustic  soda,  dissolving  in 
acidulated  w^ater,  adding  sodium  carbonate,  and  distilling  with  a  cur- 
rent of  steam.  It  is  regarded  as  identical  with  the  ehinophenol  of 
Weidel  and  Cobenzl.  (1880.) 
The  potassium  salt  of  oxychinoline,  is  readily  converted  into  the- 
methylic  ether,  niethoxy chinoline  or  chinanisoly  CjoHgNO,  by  treatment 
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