Am.  Jour.  Phari 
Mar.,  1875. 
1 24  Some  Physical  Properties  of  ^inia.  { 
These  figures  give  for  each  100  grams  of  saturated  solution  at  1 5°  C.  : 
Pure  Quinia 
dried  at  +  iio°  C. 
1st  Experiment,    ........        0-0501  grams. 
2d  "   •        .    0-0480  " 
3(1  "   .        0-0503  " 
Or  a  mean  of  0*0494  gram  of  quinia  in  each  100  grams  of  solution; 
from  which  the  author  concludes  that  the  co-efficient  of  solubility  at 
that  temperature  is  i  in  2024  ;  or  that  one  gram  of  pure  quinia  requires 
for  its  perfect  solution  at  15°  C.  rather  more  than  two  litres  of  distilled 
water. 
The  solubility  is  considerably  increased  at  100°  C,  as  stated  by 
most  authors,  and  as  is  shown  by  the  following  experiments  : 
Water  saturated  Pure  Quinia  dried 
at  ioqO  C.  at  no"  C. 
ist  Experiment,     .        .        .        64*5430  grams.  0-0870  grams. 
2d  "  ...    65-5265      "  0-0840  " 
Or  a  mean  for  each  100  grams  of  0*1314  gram;  from  whence  the 
author  concludes  that  the  co-efficient  of  solubility  of  quinia  in  water 
at  100°  C.  is  I  in  760.  Therefore  water  saturated  with  quinia  at 
100°  C.  deposits  in  cooling  to  15°  G.  nearly  two-thirds  of  the  alka- 
loid originally  dissolved. 
Solubility  in  Jlcohol. — The  author  used  absolutely  pure  and  anhydrous 
ethylic  alcohol.  One  carefully  conducted  experiment  gave  a  result 
so  nearly  concordant  with  what  is  stated  in  chemical  treatises  that  it 
was  not  repeated. 
Absolute  alcohol  saturated  Quinia  dried  at 
atisOC.  hqOC. 
41-454  grams.  19-428  grams. 
This  is  equal  to  46-866  grams  to  100  grams  of  solution,  and  the 
co-efficient  of  solubility  at  15^  C.  would  be  i  in  1*133  ;  other 
words,  I  gram  of  pure  quinia  will  dissolve  in  I'I33  gram  of  absolute 
alcohol  at  15°  C.  Several  chemists  have  mentioned  the  great  solu- 
bility of  quinia  in  alcohol.  Dragendorff  and  Wurtz  have  it  as  1  in  2, 
which  is  too  low.  The  difference,  however,  probably  depends  upon 
a  slightly  hydrated  alcohol  having  been  used,  for  the  solubility  of  quinia 
in  alcohol  decreases  rapidly  with  the  smallest  addition  of  water. 
Solubility  in  Chloroform. — lOO  grams  of  chloroform  saturated  at  15° 
C.  gave  34*177  grams  of  quinia  dried  at  110°  C,  being  equal  to  i  in 
1*926.  This  number  is  substantially  in  agreement  with  Pettenkofer's 
statement  of  55  per  cent.,  or  i  in  i*8oi.    The  co-efficient  i  in  6*58, 
