Am  jour.Pharm.|         Examination  of  9uinia  Fills.  163 
April,  1875.       1  -J 
our  sample  of  cincho-quinine  No.  4.  It  resembled  circular  No.  1  in 
its  general  appearance,  size,  etc.  ;  but,  on  its  second  page,  contained 
only  extracts  from  letters,  while  the  first  page  contained,  besides  ex- 
tracts from  letters,  the  illustration  of  a  bottle  of  cincho-quinine,  etc., 
the  following  : 
"CINCHO-QUINJNE  holds  ail  the  Important  constituents  of  bark  in  their  alkaloidal 
conditions.  It  contains  no  sulphate  of  cinchonidine,  quinidine  or  quinine,  but  the 
pure  alkaloids  cinchonidine,  quinidine,  clnchonine,  quinine,  etc  ,  without  acid  com- 
binations.   It  contains  no  substances  but  those  found  naturally  existing  in  bark. 
"  CiNCHO-QyiNiNE  is  believed  to  have  these  advantages  over  sulphate  of  qumine  . 
"  ist.  It  exerts  the  full  therapeutic  influence  of  sulphate  of  quinine,  in  the  same 
doses,  without  oppressing  the  stomach  or  creating  nausea.  //  does  not  produce  cere- 
bral distress,  as  sulphate  of  quinine  is  apt  to  do,  and  in  the  large  number  of  cases 
in  which  it  has  been  tried,  it  has  been  found  to  produce  much  less  constitutional  dis- 
turbance. 
"  2d.  It  has  the  great  advantage  of  being  nearly  iasieiesu  The  bitter  is  very  slight, , 
and  not  unpleasant  to  the  most  sensitive,  delicate  woman  or  child. 
"  3d,  It  is  less  costly  than  sulphate  of  quinine.  Like  the  sulphate  of  quinine,  the 
price  will  fluctuate  with  the  rise  and  fall  of  barks,  but  it  will  always  be  less  than  the 
lowest  market  price  of  that  salt. 
"We  now  supply  sugar-coated  cincho-quinine  pills  of  three  sizes,  namely,  i  grain, 
2  grains  and  3  grains,  in  such  quantities  as  are  wanted.  They  are  placed  in  vials 
holding  ICQ  each.    The  price  is  about  one-half  that  of  quinine  pills.    Dose  the 
same. 
EXAMINATION  OF  QUINIA  PILLS. 
BY  HENRY  TRIMBLE. 
[Read  at  the  Pharmaceutical  Meeting,  March  i6th.) 
Having  recently  met  with  some  spurious  quiriia  pills  in  the  market  of 
this  city,  I  was  induced,  at  the  suggestion  of  some  of  my  friends,  to 
make  an  examination  of  several  samples  from  different  manufacturers 
and  dealers.  The  results,  as  given  below,  strongly  indicate  that,  in  our 
present  questionable  practice  of  allowing  the  wholesale  manufacturer 
to  prepare  those  articles  which  should,  properly,  be  made  in  the  labora- 
tory of  the  individual  pharmacist,  we  must  exercise  the  most  scrupu- 
lous care  to  guard  against  impositions  which  are  sure  to  be  attempted 
on  the  profession  and  the  community  at  large.  Seven  samples  were  ob- 
tained and  examined,  six  of  them  being  from  prominent  manufacturers 
of  this  city. 
The  process  followed  was  to  dissolve  that  number  of  pills  which 
represented  five  grains  of  sulphate  of  quinia  in  about  a  fluidrachm  of  water, 
acidulated  with  a  few  drops  of  dilute  sulphuric  acid.     From  this  the  quinia 
