2  so  Salicylate  and  Carbolate  of  ^inia.  {^^1^%^^^""^' 
^'  Amer.  Jour.  Phar.,"  1874,  p.  154) ;  but  he  contends  that  the  drug, 
which  was  known  here  as  Turkey  or  Russian  rhubarb,  and  which 
came  through  Siberia  by  way  of  Kiachta,  was  obtained  from  Rheum 
palmatum  var.  Tanguticum.  His  plants  were,  in  1872-3,  collected  by 
Przewalski,  in  the  vicinity  of  Lake  Koko  Nor,  where  the  plant  was 
formerly  extensively  cultivated.- -/i^/V.,  April  3d  ;  Kegel's  Gartenflora^ 
January. 
Chemical  Examination  of  fahorandi. — M.  Byasson  has  published  in 
Rtp.  de  Phar.^  March  25,  the  results  of  his  investigation  of  jaborandi 
leaves,  from  which  it  appears  that  they  contain  a  volatile  oil,  an  acrid 
resin,  and  an  alkaloid,  to  which  the  properties  of  jaborandi  are  due. 
It  was  prepared  by  concentrating  the  tincture,  mixing  the  aqueous 
filtrate  with  lime,  and  exhausting  the  desiccated  mass  with  chloroform, 
which  left  it  as  a  viscous  aromatic  mass,  soluble  in  chloroform,  ether, 
absolute  alcohol,  ammoniacal  water  and  dilute  acids.  The  author  pro- 
posed the  name  of  jaborandina  ;  but  since  this  name  has  been  already 
appropriated  (see  "Amer.  Jour.  Phar.,"  May,  p.  214),  M.  Holmes 
suggests  to  call  it  pilocarpina. — Ibid.^  April,  p.  174. 
A.  W.  Gerrard  has  experimented  with  jaborandi  bark,  and  has  ar- 
rived at  similar  results.  The  alkaloid  is  prepared  by  evaporating  the 
aqueous  solution  of  the  alcoholic  extract  to  the  consistence  of  a  soft 
extract,  adding  ammonia  in  slight  excess  and  exhausting  with  chloro- 
form. Half  a  grain  was  administered  and  produced  the  full  effects  of 
the  drug.  The  bark  contains  also  tannin. — Pharm.  your,  and  Trans. ^ 
April  17  and  May  i. 
Chloral  Hydrate. — Mr.  Ore  states  :  A  very  small  quantityof  carbonate 
of  sodium  is  sufficient  to  remove  the  acidity  of  chloral  hydrate  in  solution 
and  to  render  it  alkaline.  There  is  a  slight  disengagement  of  carbonic 
acid,  and  some  chloride  of  sodium  is  formed.  Comparative  experiments 
have  shown  that,  whilst  chloral  hydrate  retards  the  coagulation  of  blood, 
chloral  hydrate,  thus  rendered  alkaline  by  carbonate  of  sodium,  entirely 
prevents  it.  The  addition  of  the  soda,  he  believes,  does  not  at  all  in- 
terfere with  the  anaesthetic  properties  of  the  chloral. — Journal  de  Phar- 
made.  
THE  SALICYLATE  AND  CARBOLATE  OF  QUINIA.- 
BY    JULIUS  JOBST. 
In  a  communication  to  the  "  Pharmaceutische  Zeitung  "  (No.  11, 
1875),  Schering  states  that  salicylic  acid  forms  with  quinia  a  salt  in- 
■^"Neues  Repertorium  fiir  Pharmacie,"  xxiv,  193. 
