'^"'•fc?7t'"''}  Contributions  from  the  School  of  Pharmacy,  etc.  483 
a  second  operation,  after  extracting  with  chloroform  as  before,  the 
alkaline  solution  was  extracted  with  amylic  alcohol  ;  the  chloroform 
giving  a  residue  of  I7'4  milligrams  and  the  amylic  alcohol  giving  1*4 
milligrams,  making  a  total  of  i8*8  milligrams.  In  a  third  operation, 
the  alkaline  solution  (previously  washed  with  chloroform  while  acid) 
was  three  times  exhausted  with  chloroform,  and  then  extracted  with 
amylic  alcohol,  when  the  residue  of  all  the  chloroform  weighed  iq'i 
milligrams,  and  the  amylic  alcohol  left  no  appreciable  residue.  Hence 
it  appeared  that  the  use  of  amylic  alcohol,  the  solvent  preferred  for 
morphia  by  DragendorfF"^  is  not  indispensable  if  sufficient  chloroform  be 
used.  In  another  operation,  the  chloroform  solution  of  alkaloid  ob- 
tained as  previously  was  extracted  with  water,  acidulated  by  sulphuric 
acid,  and  the  aqueous  sulphate  titrated  with  Mayer's  volumetric  solu- 
tion, when  1*2  cub.  cent,  of  this  solution  were  required  to  complete 
the  precipitate.  Each  cub.  cent,  precipitating  0'020  of  morphia,  24 
milligrams  of  alkaloid  were  indicated. 
The  traces  of  other  opium  alkaloids  could  not  appreciably  vary  the 
results,  which  are  only  presented  as  pretty  nearly  approximate.  The 
volumetric  method  was  less  satisfactory  than  the  others.  Taking  the 
mean  of  the  other  three  results  we  have  (i8+i8'4+i9*i)  -^-3  =  18*5 
milligrams,  or  0*28  grains  alkaloid,  from  the  fluidounce  of  syrup. 
The  qualitative  reactions  for  morphia  were  obtained  from  the  residue 
with  iodic  acid  and  starch,  with  nitric  acid  (followed  by  stannous  chlor- 
ide), with  ferric  chloride,  platinic  chloride,  sulpho-molybdic  acid,  tan- 
nic acid,  and  with  sugar  and  sulphuric  acid. 
VII.  Examination  of  Deposits  from  Pharmacopceial  Fluid 
Extracts  of  Cinchona,  Ergot  and  Hyoscyamus.  By  C.  S. 
Johnson,  P.  C. 
The  deposits  examined  were  obtained  by  Messrs.  Eberbach  &  Co., 
pharmacists,  at  Ann  Arbor,  Mich.,  from  fluid  extracts  of  their  own 
manufacture.    The  fluid  extracts  were  made  strictly  according  to  the 
Pharmacopoeia "  of  1870,  from  carefully  assorted  drugs,  and  were 
perfectly  clear  at  first.  They  were  stored  in  large  bottles  secluded 
from  the  light,  in  the  cellar,  for  two  or  three  weeks,  when,  as  they 
were  decanted,  the  deposits  were  drained  upon  muslin,  and  then  kindly 
furnished  for  the  examination  here  reported. 
"  Werthbestimmung  Starkwirkender  Droguen."  85. 
