484  Contributions  from  the  School  of  Pharmacy,  etc.  {^'"•fcs^s'''"' 
The  deposits  were  first  washed  on  the  filter,  with  cold  water,  until 
the  washings  were  tasteless  and  colorless. 
The  washed  deposit  from  fluia  extract  of  cinchona  was  dark  brown,, 
soft  and  of  impalpable  fineness,  and  decidedly  bitter  and  astringent  to> 
the  taste.  Under  a  careful  microscopical  examination,  it  was  found 
to  be  composed  largely  of  cellular  material.  By  this  inspection  it  was 
judged  that  the  cellular  matter  constituted  at  least  two-thirds  of  its 
bulk.  A  solution  obtained  by  acidulated  dilute  alcohol  gave  abundant 
general  reactions  for  alkaloids.  The  entire  deposit  did  not  respond  to 
the  thalleioquin  test  for  quinia  ;  but  on  washing  it  with  ammonia  and 
extracting  the  filtrate  with  ether,  a  residue  was  obtained  giving  clear 
indication  of  quinia  by  this  test.  The  acidulated  water  solution  was- 
precipitated  by  ammonia  ;  this  precipitate,  corresponding  in  solubilities 
to  cinchonia,  was  abundant.  Also,  tests  for  quino-tannic  and  quinic 
acids  were  obtained.  The  ash  of  the  deposit  was  rich  in  potassium 
compounds.  The  washed  and  dried  deposit  was  assayed  for  alkaloids,, 
according  to  Hager's  method  for  treating  bark,  and  a  result  of  2J  per 
cent,  of  total  alkaloids  obtained.  In  this  determination,  16  grams  of 
the  material  was  taken  ;  the  first  precipitate  by  soda  was  darker  in  color 
than  that  usually  obtained  in  treating  bark,  but  after  dissolving  in  acid- 
ulated water  the  second  precipitate  by  soda  was  pale  and  weighed  for 
result. 
The  deposit  from  fluid  extract  of  ergot  was  black,  of  oily  plastic  con- 
sistence, and  had  the  odor  of  ergot.  By  exhaustion  with  ether,  con- 
siderable oil  was  obtained.  The  residue  of  this  treatment  was  found, 
under  the  microscope,  to  consist  of  mixed  cellular  and  amorphous  mat- 
ter. The  water  solution  of  the  same  residue  gave  an  abundant  yel- 
lowish-white precipitate  with  acetate  of  lead  ;  but,  after  removing  the 
lead,  no  precipitate  was  obtained  with  mercuric  chloride  (Wenzell's 
method),  and  no  definite  results  as  to  alkaloids  were  reached. 
The  deposit  from  fluid  extract  of  hyoscyamus  had  the  appearance  of 
soft  tar,  and  a  strong  odor  of  hvoscyamus.  By  distillation  from  the 
water-bath,  a  considerable  portion  of  empyreumatic  oil  was  obtained. 
Scarcely  any  cellular  matter  was  found  by  microscopical  examination. 
The  ash  from  the  deposit  was  rich  in  potassium  nitrate.  No  alkaloid- 
was  found. 
