Am.  Jour.  Pharm.  ) 
April,  1921.  J 
New  Source  of  Santonin. 
Isodulceous  Solutions,  i.  e.,  Solutions  Possessing  the  Same  Degree  of 
Sweetness. 
Sum.  of  Sach. 
Sugar  Saccharin  Dulcin  Saccharin  &  Dulcin       &  D.ulcin 
Gm.  in  i  Lit.  Mg.  in  I  Lit.  Mg.  in  i  Lit.  Mg.  in  I  Lit.       Mg.  in  i  Lit. 
10  20  30 
20  30  55 
30  55  120 
40  100  290  55             30  85 
50  150  480  55              55  no 
60  190  665  100             55  155 
.    70  28b  855  150              55  205 
80  3/0  1050  100             55  245 
90  450  1250  190            120  310 
100  535  1430  280            120  400 
Of  added  interest  is  the  observation  that  the  sweet  taste  of 
solutions  containing  saccharin  and  dulcin  is  more  agreeable  than 
that  of  a  solution  of  saccharin  alone. 
A  NEW  SOURCE  OF  SANTONIN .* 
By  Henry  G.  Greenish  and  Constance  E.  Pearson. 
A  few  weeks  ago  a  small  quantity  of  the  leaves  of  a  species 
of  Artemisia  was  referred  to  the  Pharmacy  Research  Laboratory 
for  identification  and  for  examination,  more  particularly  for  the 
possible  presence  of  santonin.  The  material  consisted  almost  en- 
tirely of  very  hairy,  much  sub-divided  leaves.  They  were  identified 
at  the  herbarium  of  the  Royal  Botanic  Gardens,  Kew,  as  being* 
derived  from  Artemisia  brevifolia,  Wallich.  This  plant  is  described 
by  Hooker,1  under  the  name  of  A.  maritima,  Linn.,  and  the  follow- 
ing details  are  taken  from  his  description:  The  plant  produces  a 
woody,  branched  rootstock  with  woody  or  wiry  stems,  6  to  18 
inches  high,  erect  or  ascending  and  much  branched  from  the  bases. 
The  leaves  are  half  to  two  inches  long,  ovate,  2-pinnatisect,  often 
quite  white,  with  very  many  small,  spreading,  linear,  obtuse  seg- 
*  Contribution  from  the  Pharmacy  Research  Laboratory  of  the  Pharma- 
ceutical Society.  Reprinted  from  the  Pharm.  Jour,  and  Pharmacist,  January 
1,  1921. 
1  Flora  Indica,  Vol.  iii,  p.  322. 
