LIQUOR  OPII  COMPOSITUS. 
57 
half  grains,  is  therefore  adopted  as  the  standard  weight  of  thirty- 
cubic  centimetres,  or  one  fluidounce  of  a  properly  made  prepara- 
tion, measured  at  17°  G.=62'6  F. 
This  would  indicate  the  following  composition  or  formula  for 
each  30  c.c.  or  1  fluidounce  of  liquor  opii  compositus  : 
Depurated  solution  of  opium  containing, — 
4  grs.  morphia,  14c.c.=15-047grms.,=232'17grs.=51-887p.c. 
Stronger  alcohol,  13  c.c.-=10-686         =164-91  "  =36'848  " 
Purif.  chloroform,  lc.c.=  1499    "    =  2343  "  =  5469  " 
Acetic  ether,        2 c.c.--  1-768        =  27-29  "  =  6-096 
30c.c.=29-000  "  =447-50  "  =100-000  " 
When  it  shall  have  been  determined  by  the  assay  how  many 
fluidounces  of  the  finished  preparation  the  solution  will  yield, 
this  number  of  fluidounces  is  to  be  multiplied  by  447*5,  or  the 
number  of  grains  in  each  fluidounce  when  finished,  and  the  pro- 
duct will  be  the  weight  in  grains  of  the  finished  preparation. 
¥his  number  of  fluidounces  multiplied  by  164*91,  or  the  number 
of  grains  of  alcohol  in  each  finished  fluidounce,  will  give  the 
weight  in  grains  of  the  whole  quantity  of  alcohol  required.  But 
a  constant  quantity  of  1574  grains  of  the  alcohol  is  required  in, 
and  has  already  been  added  to  the  watery  solution  before  the 
assay,  and  therefore  this  quantity  must  be  subtracted  from  the 
whole  quantity  required,  and  the  remainder,  only,  must  be  taken 
for  the  final  adjustment.  This  same  number  of  fluidounces  of 
the  finished  preparation  multiplied  by  23*13,  or  the  number  of 
grains  of  purified  chloroform  in  each  finished  fluidounce,  will  give 
the  whole  weight  in  grains  of  chloroform  required.  The  same 
number  of  fluidounces  of  the  finished  preparation  multiplied  by 
27-29,  or  the  number  of  grains  of  acetic  ether  in  each  finished 
fluidounce,  will  give  the  whole  weight  in  grains  of  acetic  ether 
required.  These  calculations  are  really  simple,  and  may  be  use- 
fully illustrated  by  continuing  the  supposed  case  taken  to  illus- 
trate the  application  of  the  assay. 
The  182-72  grains  of  morphia  found  to  be  in  the  remainder 
of  the  solution  assayed  (the  16  fluidounces  or  480  c.c),  divided 
by  4,  gives  45-75  fluidounces  or  1372  c.c.  as  the  measure  for  the 
finished  liquor  opii  compositus  when  it  shall  contain  the  required 
