136 
ON  ZINC  SULPHO-PHENATE. 
useful.  Its  solubility  in  glycerin  and  in  alcohol  will  enable  it 
to  be  used  in  lotions  with  advantage. 
Sulplio-Carholate  of  Lime  is  readily  made  by  the  same  pro- 
cess, and  in  this  case  the  free  sulphuric  acid  is  also  separated  in 
the  process  as  sulphate  of  lime.  The  proportion  of  the  acid  is 
much  larger  in  this  salt  than  in  some  others.  It  is  also  soluble 
in  less  than  its  weight  of  water  at  60°  Fahr.,  soluble  in  alcohol 
and  to  some  extent  in  glycerin. 
SulpJio-Carholate  of  Quinia. — When  crude  free  sulpho-car- 
bolic  acid  is  saturated  with  pure  quinia,  an  oil  like  compound  is 
formed,  which  gradually  dissolves  in  the  water  and  has  a  dark 
brown  color.  Supposing  the  impurity  of  the  acid  was  the  cause 
of  this  condition,  an  alcoholic  solution  of  sulpho-carbolate  of  lead 
was  mixed  with  one  of  sulphate  of  quinia  in  alcohol,  the  solution 
filtered  from  the  sulphate  of  lead  and  spontaneously  evaporated, 
when  the  quinia  salt  separated  in  the  same  oily  condition,  but 
on  standing  some  days  it  became  a  nearly  white  solid,  with  a 
crystalline  structure.  It  is  exceedingly  bitter,  not  very  soluble 
in  water,  but  soluble  in  alcohol. 
ON  ZINC  SULPHO-PHENATE  * 
By  Dr.  Hager. 
The  preparation  of  this  salt  presents  no  difficulties  if  pure 
crystallized  phenol  and  pure  monohydrate  of  sulphuric  acid  are 
operated  on.  Equal  weight  parts  of  both  are  digested  at  about 
125°  F.  for  two  to  three  days.  When  the  phenol  is  pure  a  clear,  ^ 
yellowish,  thick  liquid  is  obtained,  which  on  cooling  deposits 
conglomerations  of  crystals  (probably  uncombined  phenol),  but 
which  soon  congeals  to  a  white  crystallized  mass.  Although  all 
conditions  are  present  to  combine  all  the  sulphuric  acid  with  the 
phenol,  yet  there  remains  always,  and  no  matter  how  long  the 
digestion  may  be  continued,  a  surplus  of  about  10  per  cent,  sul- 
phuric acid.  For  this  reason  it  is  advisable  to  mix  120  parts  of 
sulphuric  acid  to  every  100  parts  of  phenol.    After  two  or  three 
*  Translated  from  Dr.  Hager's  Pharmaceutischer  Centralhalle,  No.  1, 
1870  (January  6,  1870),  by  Dr.  F.  Hoffmann. 
