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STRYCHNINE  AN  ANTIDOTE  TO  CHLORAL. 
and  savorer,  to  each  ounce  of  the  mixture  one  drachm  of  spirit 
of  wine,  to  which  has  been  added  a  drop  of  essence  of  lemon, 
the  same  quantity  of  essence  of  almonds,  and  a  trifle  of  oil  of 
cassia. 
Thus  is  the  melange  completed,  and  of  so  agreeable  a  flavor  is 
the  result,  that  to  most  palates  it  would  be  found  to  acquit  itself 
creditably  in  comparison  with  an  average  custard. 
Emulsio. 
— Pliarm.  Journ.,  London,  April,  1870. 
STRYCHNINE  AN  ANTIDOTE  TO  CHLORAL. 
Dr.  Liebreich,  the  discoverer  of  the  therapeutic  action  of 
chloral,  has  been  seeking,  and  announces  that  he  has  found  the 
antidote  to  this  powerful  agent. 
He  first  of  all  established  the  fact  that  chloral  diminishes  the 
eff'ects  of  strychnine,  provided  it  is  given  very  promptly  after 
the  exhibition  of  the  poisonous  alkaloid. 
A  much  more  important  result  has  been  obtained  in  another 
series  of  experiments  which  Dr.  Liebreich  made  subsequently  to 
this,  and  which  had  for  its  object  to  demonstrate  the  efi*ect  of 
strychnine  upon  animals  poisoned  by  fatal  doses  of  chloral.  The 
following  is  an  apparently  conclusive  experiment: 
Two  rabbits  received  each  2  grams  (about  30  grains)  of  chloral. 
After  half  an  hour  both  were  in  a  condition  of  profound  nar- 
cotic sleep;  the  muscular  relaxation  was  such  that  they  appeared 
as  if  dead,  the  respiration  being  feeble  and  slow.  A  milligram 
and  a  half  (less  than  one  fortieth  of  a  grain)  of  nitrate  of 
strychnia  was  injected  into  one  of  them.  In  ten  minutes  after 
this  operation  the  respiration  began  to  resume  its  activity,  the 
animal  moved  when  irritated,  but  there  were  no  convulsions ; 
the  muscles  recovered  their  tonicity ;  when  the  feet  of  the  ani- 
mal were  drawn  out  he  drew  them  in  again.  Two  hours  after- 
wards the  rabbit  was  sitting  up,  and  four  hours  after  the  injection 
he  was  completely  restored  to  his  usual  condition.  The  other 
rabbit,  on  the  contrary,  which  had  not  received  any  strychnine, 
was  dead  two  hours  and  a  half  after  the  administration  of  the 
chloral. 
A  third  rabbit,  to  which  no  chloral  had  been  given,  but  only 
