Amju°ne'iwiarm'}    Developments  in  Organic  Compounds. 
271 
DOUBLE  LINKAGE. 
According  to  Loew,  "  bodies  with  double  linkage  are  more  toxic 
than  the  corresponding  saturated  ones." 
For  example,  Dr.  Miessner  has  shown  that  those  engaged  in  the 
preparation  of  allyl  alcohol 
CH„ 
II 
CH 
1 
CH2OH 
suffer  serious  toxic  symptoms,  while  the  corresponding  saturated 
propyl  alcohol 
CH3 
I 
CH, 
I 
CH,OH 
is  non  toxic. 
The  trebly  linked  di-iodo-acetyliden 
CI 
CI 
is  an  energetic  poison,  likewise  allylamin  (CH2  =  CH  —  CH2  NH2) 
also  vinylamin  (CH2  =  CH  .  NH2). 
The  same  influence  is  noticeable  in  the  non-toxic  singly  linked 
alkyl  groups  of  cholin  as  compared  to  the  very  toxic  doubly  linked 
in  neurin. 
Cholin  (CH3)3N< 
Neurin  (CH,)8N/ 
Allyl  mustard  oil 
CH2  — CH2OH 
OH 
/CH  =  CH2 
NOH 
Tri-  methyl-  oxy.  e  thy  I 
ammon-hycL  rcxid 
Iri-  methyl-vinyl- 
am  mon-hydroxid. 
CH2 
II 
CH 
CH9—  NCS 
acrolein 
