Aloctober,^90hm'}    American  PJiarmaceutical  Association.  489 
up  the  puzzling  behavior  of  Gaze's  berberine.  It  does  not  absorb 
carbon  dioxide  because  it  is  not  the  free  base  but  a  salt  of  it.  It 
does  not  take  up  any  acid  when  it  is  taken  up  by  acid  and  precipi- 
tated with  potassium  iodide  or  Wagner's  or  Mayer's  reagent,  because 
it  simply  interchanges  its  acid  with  the  potassium  iodide  falling  out 
as  a  hydriodide, leaving  an  equivalent  amount  of  potassium  chloride 
in  solution.  Silver  nitrate  reacting  with  the  potassium  chloride 
exactly  as  it  does  with  potassium  iodide  does  therefore  not  show 
any  consumption  of  the  latter  salt. 
The  Alkaloids  of  Glaucium  Flavum. 
By  R.  Fischer. 
The  author  isolated  from  this  plant  two  alkaloids,  protopine, 
identified  by  analysis,  m.  p.,  and  crystallographic  form,  and  another 
alkaloid,  undoubtedly  identical  with  the  glaucine  of  Probst,  although 
the  latter  investigator  dealt  with  a  very  impure  substance.  Pure 
glaucine  crystallizes  from  ethereal  solutions  in  large,  well  defined 
crystals  belonging  to  the  rhombic  system.  It  melts  at  H9°-I20° 
and  dissolves  readily  in  alcohol,  ether,  chloroform,  acetone  and 
acetic  ether;  in  water  it  is  but  slightly  soluble.  Glaucine  is  a  very 
weak  base.  It  is  optically  dextrorotatory  [L]d,  being  ~f  1 1 3.3  for 
approximately  5  per  cent,  solution.  Its  reactions  with  general 
alkaloidal  reagents  are  very  delicate  and  characteristic.  The  pre- 
paration of  crystalline  gold  and  platinum  salts  did  not  succeed  on 
account  of  the  strong  reducing  action  of  the  base.  A  crystalline 
mercury  salt,  however,  was  obtained,  melting  at  I30°-I40°. 
The  empirical  formula  of  glaucine  was  declared  to  be  C21H25N04. 
The  analyses  of  the  hydrochlorate  and  hydrobromate,  both  well 
defined  crystalline  substances,  corroborated  these  results.  Glaucine 
is  a  tertiary  base,  containing  four  methoxyl  groups.  The  substitu- 
tion product,  C17H13(OH)4NHI,  was  obtained  as  a  crystalline  body 
and  described. 
The  Alkaloids  of  Eschscholtzia  Californica. 
By  R.  Fischer. 
Contrary  to  the  results  of  Bardet  &  Adrian  the  author  did  not 
find  any  morphine  in  this  drug.  Instead,  protopine,  /9  homocheli- 
donine  and  y  homochelidonine  were  identified  by  analyses  as  well 
as  by  m.  p.  and  crystallographic  measurements. 
