2o6 
Pure  Emetia. 
(  Am.  Jour.  Fharm. 
(      April,  1880. 
acid,  to  an  open  sore.  The  child  immediately  fell  asleep,  and  died  a 
few  hours  later. — Pharm.  Ztg.^  Feb.  7,  1880,  p.  78. 
As  an  Antidote  for  Carbolic  Acid  Intoxication,  caused  by  con- 
tinued external  application  of  a  5  per  cent,  solution  of  the  acid,  Son- 
neberg  recommends  sodium  sulphate,  5  to  8  grams  of  which  he  admin- 
istered in  200  grams  of  water  to  adults,  and  2  to  5  grams  in  200  grams 
of  water  to  children.  The  urine  is  at  first  dark  e;reen,  and  has  a 
slightly  brownish  tint,  but  soon  acquires  again  its  normal  color,  when 
the  carbolic  acid  application  may  be  continued. — Ztschr.  d.  Allg,  Oest, 
Jpoth.  Ver.^  Jan.  20,  1880,  p.  43,  from  Apoth.  Ztg. 
Arsenic  in  the  Animal  Organism. — In  contradiction  to  Scolo- 
subofF's  statements.  Prof.  E.  Ludwig  claims  as  the  result  of  numerous 
chemical  analyses  made  by  him,  that  in  chronic  as  well  as  in  acute 
arsenical  poisoning  the  quantity  of  arsenic  traceable  in  the  brain  is  very 
minute,  while  much  larger  (frequently  90  times  as  large)  quantities  are 
found  in  the  liver;  and  he  therefore  recommends  the  liver,  and  incases 
of  acute  poisoning,  the  kidnevs,  as  the  portions  of  the  body  most  suit- 
able for  legal  chemical  investigations. — Pharm.  Post^  Jan.  16,  1880, 
p.  25. 
PREPARATION  AND  PROPERTIES  OF  PURE  EMETIA. 
By  Dr.  Podwyssgtzki. 
(Translated  and  abridged  from  "  Pharm.  Ztschr.  f.  Russl 1880,  p.  i-8,  by  Louis 
VON    COTZHAUSEN,  Ph.G.) 
I.  Preparation. — Either  one  of  the  two  following  methods  yields 
satisfactory  results  : 
1st  method. — Treat  the  powdered  ipecacuanha  first  with  ether  and 
then  with  petroleum  benzin,  in  order  to  remove  the  liquid  oil,  the  white 
fatty  or  waxy  matter  and  those  coloring  matters  which  are  soluble  in 
the  solvents  named,^  then  extract  the  powdered  root  two  or  three  times 
successively,  at  a  moderate  heat,  with  85  per  cent,  alcohol,  without 
adding  any  acid  ;  evaporate  the  mixed  tinctures  to  a  syrupy  consistence, 
add  after  cooling  a  very  concentrated  solution  of  as  much  ferric  chloride 
as  corresponds  to  from  10  to  13  per  cent,  of  the  weight  of  the  powdered 
ipecac  used,  mix  the  mass  well,  add  sodium  carbonate  in  excess,  boil 
the  mass  in  a  flask  on  a  water-bath  with  successive  small  portions  of 
^Some  ipecacuanhas,  yielding  much  emetia,  contain  a  principle  soluble  in  ether, 
crystallizing  in  straw  yellow  needles  and  forming  with  barium  hydrate  and  with 
alkalies  purple  compounds  5  the  principle  might  be  called  erythrocephalein. 
