Am.  Jour.  Pharm. 
May,  1880. 
Varieties, 
perature  of  ioo°F.,  for  about  an  hour,  before  putting  the  liquid  into 
the  dialyzer. 
(9,  — In  this  experiment  the  oxide  of  iron  and  hydrochloric  acid, 
in  the  proportion  for  forming  ferric  chloride,  were  boiled  together  for 
several  minutes,  and  the  liquid  after  cooling  was  put  into  the  dialyzer. 
At  the  end  of  two  days  a  trace  of  iron  had  passed  through  the  septum, 
but  not  more  than  in  the  preceding  experiment. 
The  hydrochloric  acid  in  these  experiments' was  greatly  in  excess  of 
that  usually  present  in  the  free  state  in  the  stotnach,  which,  according 
to  Lehmann,  is  about  '125  per  cent. 
A  suggestion  having  been  made  that  the  colloidal  iron  of  dialyzed 
iron,  although  not  diffusible  when  brought  into  a  state  of  apparent  solu- 
tion with  hydrochloric  acid,  even  when  this  is  much  in  excess  of  what 
is  required  for  such  solution,  might  be  taken  up  by  the  albuminoids  in 
the  stomach  and  thus  rendered  assimilable,  experiments  were  made  in 
'Hat  direction. 
(9,  ^.) — A  dilute  solution  of  albumen  v/ith  hydrochloric  acid  was 
digested  for  two  hours  with  dialyzed'  iron  at  ioo°F.,  and  then  left  in  a 
dialyzer  for  two  days,  but  no  iron  was  found  in  the  diffusate. 
(9,y.) — A  peptone  was  prepared  by  dissolving  50  grains  of  coagu- 
lated albumen  with  2  grains  of  pepsin  in  500  grains  of  i  per  cent,  dilute 
hydrochloric  acid,  adding  50  grains  of  dialyzed  iron,  and  digesting  them 
together  for  two  hours  at  ioo°F.  This  was  put  into  a  dialyzer  for 
two  days,  but  here  again  not  a  trace  of  iron  was  found  in  the  difFusate. 
In  view  of  these  results  it  can  hardly  be  conceived  that  dialyzed  iron 
should  be  an  active  or  efficacious  medicine.  At  any  rate  it  remains 
for  those  who  advocate  its  use  to  suggest  a  theory  by  which  medicinal 
activity  may  be  reasonably  ascribed  to  a  substance  having  the  proper- 
ties which  this  preparation  has  been  proved  to  possess. — Pharm.  your, 
and  Trans.  [London],  March  6,  1880. 
VARIETIES. 
Bromhydrate  of  Morphia.— This  is  more  soluble  in  water  and  is  twice  as  power- 
ful as  the  sulphate.  It  combines  the  sedative  effects  of  the  bromine  with  the  ano- 
dyne properties  of  the  morphia.  It  is  not  so  dangerous,  and  it  is  not  so  apt  to  be 
followed  by  unpleasant  symptoms.  It  is  the  drug  especially  for  irritative  aftections 
of  the  spinal  cord. — Journal  de  Therapeutique^  from  Western  Lancet,  Jan.,  1880. 
