Am.  Jour.  Pharm. 
June,  1880. 
Pharmaceutical  Notes, 
299 
AN  IMPROVED  FORMULA  FOR  CHLORODYNE. 
By  R.  De  Puy. 
The  formula  for  preparing  chlorodyne,  adopted  by  the  American 
Pharmaceutical  Association,  yields  a  very  unpharmaceutical  mixture,, 
and,  when  tried,  has  failed  to  give  satisfaction.  The  formula  which  I 
have  been  using  for  the  last  two  years  has  given  entire  satisfaction,  and„ 
if  the  ext.  liquorice  be  of  good  quality,  does  not  separate.  It  is  as  fol- 
lows : 
Purified  chloroform,      .  . 
4  fl.  oz. 
Stronger  ether,  .... 
I  fl.  oz. 
"  alcohol. 
4  fl.  oz.  s 
Molasses,  ..... 
4  fl.  oz. 
Ext.  liquorice,  B.  P., 
2^  troy  oz. 
Morphia  hydrochlorate, 
8  grains. 
Oil  peppermint, 
16  minims. 
Glycerin,      .           .           .           .  . 
17J  fl.  oz. 
Acid  hydrocyanic,  2  per  cent.,  . 
2  fl.  oz. 
Dissolve  the  morphia  and  oil  peppermint  in  the  alcohol,  and  mix  the 
chloroform  and  ether  with  this  solution.  Mix  the  ext.  liquorice  with 
the  molasses  by  applying  a  gentle  heat,  let  cool,  and  to  this  add  the 
glycerin.  Shake  these  two  mixtures  together,  and  lastly  add  the  hydro- 
cyanic acid,  and  again  shake  well.  This  is  the  American  Pharmaceu- 
tical Association  formula,  having  glycerin  substituted  for  syrup,  which 
I  consider  in  every  way  an  improvement. 
—  Canad.  Pharm.  yow^n..^  May,  1880. 
PHARMACEUTICAL  NOTES. 
By  Robert  F.  Fairthorne,  Ph.G. 
An  Expeditious  Method  for  Making  Mercurial  Ointment. — Many- 
suggestions  have  been  made  for  overcoming  the  difficulty  experi  ■ 
enced  in  the  manufacture  of  mercurial  ointment  of  the  officinal 
strength  of  the  U.  S.  Pharmacopoeia.  Some  of  the  plans  proposed  are 
decidedly  objectionable,  such,  for  instance,  as  the  introduction  of  tur- 
pentine or  sulphur,  also  the  addition  of  old  and  rancid  ointment,  or 
exposure  of  the  ointment  until  rancidity  occurs,  so  that  it  becomes  a 
desideratum  with  the  trade  that  some  practical  and  unobjectionable 
means  should  be  adopted  whereby  labor  would  be  saved  and  an  oint- 
ment made  that  would  be  bland  and  non-irritant  in  character.  Such 
a  method  I  have  now  to  propose,  which,  doubtless,  will  give  others  the 
