108 
PHARMACEUTICAL  GLEANINGS. 
Sulphate  of  Quinidine  in  Intermittent  Fever. — Dr.  J.  S.  Dor- 
sey  Cullen,  one  of  the  Assistant  Physicians  at  the  Philadelphia 
Hospital,  reports  in  Hay's  Journal  for  January,  180  cases  of 
intermittents  treated  with  sulphate  of  quinidia.  The  patients 
were  mostly  Irish  and  German  laborers  ;  in  nearly  every  case  a 
purgative  was  administered  before  commencing  with  the  quini- 
dine ;  the  dose  was  generally  three  grains  every  hour  for  five 
hours  preceding  the  period  for  the  recurrence  of  the  chill.  Of 
the  180  cases,  111  were  of  the  quotidian  type,  35  of  the  tertian, 
and  31  tertain  and  quotidian.  In  129  cases,  the  chill  was  averted 
by  15  grains  of  the  salt,  without  a  return  of  it.  After  the 
arrest  of  the  chill,  the  patients,  in  every  instance,  took  an  infu- 
sion made  of  serpentaria,  gentian  and  cinchona,  with  citrate  of 
iron.  Dr.  Cullen  is  so  well  convinced  of  the  efficacy  of  sulphate 
of  quinidia,  that  he  employs  it  instead  of  the  quinia  salt  for  the 
uses  stated,  as  its  lower  price  makes  it  an  object  in  the  economy 
of  the  hospital. 
New  Hemostatic  M.  Hannon,  of  Belgium,  believes  the  fol- 
lowing composition  to  possess  powerful  haemostatic  properties 
superior  to  any  other  known,  whether  applied  locally  or  taken 
internally,  viz  : — Take  of  benzoic  acid  1  part,  alum  3  parts,  ergo- 
tine  3  parts,  water  20  parts,  boil  them  together  for  thirty  minutes 
in  a  porcelain  capsule,  constantly  stirring  the  mass  and  replacing 
the  evaporated  moisture.  Finally,  it  is  concentrated  to  the  con- 
sistence of  an  extract,  with  constant  stirring  to  prevent  the  separa- 
tion of  the  benzoic  acid  by  crystallization,  and  when  finished,  has 
a  brown  color  and  strong  astringent  taste. 
It  is  applied  externally  in  the  form  of  a  plaster  over  the  seat 
of  the  hemorrhage.  For  its  internal  use,  as  in  hemoptysis,  it  is 
sufficient  to  make  up  the  ingredients  mixed  together  directly  into 
pills,  thus:  powdered  benzoic  acid  15  grs,,  powdered  alum  and 
ergotine,  of  each  45  grs.,  mix  and  form  into  16  pills,  one  of  which 
is  to  be  given  every  two  hours. — Rays'  Journal. 
Thein  and  Qaffein. — Prof.  Albers  having  made  a  series  of  ex- 
periments on  frogs  and  rabbits  with  the  citrates  of  caffein  and 
thein,  has  arrived  at  the  following  results  in  reference  to  their 
physiological  action. 
1st.  Both  are  capable  of  producing  tetanic  rigidity  in  frogs, 
