IDENTITY  OF  SANGUINARINE  AND    CHELERITHRINE.  41 
proceed  at  once  to  the  second  part  of  the  process — varnishing 
the  pills. 
Make  a  solution  of  balsam  of  Tola  in  three  parts  of  ether. 
Place  the  pills  in  a  porcelain  capsule,  pour  on  them  a  portion  of 
the  ethereal  tincture,  and  impress  a  rapid  movement  of  rotation, 
that  the  pills  may  be  moistened  on  every  side,  and  that  the  ether 
may  evaporate  rapidly.  As  soon  as  the  pills  begin  to  stick 
together,  throw  them  on  a  dry  surface,  separating  those  that  are 
agglutinated  and  leave  them  exposed  to  the  air  for  twenty-four 
hours  ;  then  dry  them  over  a  stove  at  a  gentle  heat. 
It  is  well  to  give  them  a  second  coating  of  varnish.  Blancard 
puts  them  in  a  bottle  with  a  stopper  covered  with  silver,  which  is 
at  once  tarnished  by  the  vapor  of  free  iodine. 
Each  pill  contains  about  one  grain  of  iodide  of  iron,  and  one- 
fifth  of  a  grain  of  powdered  iron  on  its  surface.    Two  to  four 
pills  daily  is  the  ordinary  dose  in  chlorotic,  scrofulous,  tubercu- 
lous, and  syphilitic  diseases.  C.  E.. 
Virginia  Medical  and  Surgical  Journal,  Oct.,  1855. 
ON  THE  IDENTITY  OF  SANGUINARINE  AND  CIIELERITHRINE, 
AND  ON  THE  DIRECT  DETERMINATION  OF  NITROGEN. 
By  Dr.  James  Shiel,  bf  St.  Louis,  Mo. 
I  have  used  a  small  portion  of  hydrochlorate  of  Chelerithrine 
which  I  received  in  1843  from  my  friend,  Prof.  II.  Will  of  Gies- 
sen,  and  which  the  discoverer  of  that  alkaloid  had  prepared  him- 
self, to  make  a  few  analytical  experiments  as  to  its  composition. 
As  the  salt  was  not  found  to  be  free  from  impurities,  it  was 
dissolved  in  water,  precipitated  by  ammonia,  washed,  dried,  dis- 
solved in  ether,  the  filtered  solution  treated  with  animal  char- 
coal, and  the  chelerithrine  precipitated  with  a  solution  of  pure 
sulphuric  acid  in  ether ;  the  sulphate  of  chelerithrine  was 
washed  with  ether,  dried  and  dissolved  in  water,  when  it  yielded 
with  ammonia  a  precipitate  of  pure  Chelerithrine,  which  abso- 
lutely showed  the  same  properties  and  behaviour  as  Sanguina- 
rine. 
Of  the  pure  substance  dried  at  105°  C, 
0.356  grammes  burned  with  oxyd  of  copper  and  oxygen,  fur- 
