EXTRACTUM  JJVM  URSI  ET  LUPULIM  FLUIDUM.  523 
which  rub  to  a  bright  red  powder.  From  its  acid  combinations 
it  is  precipitated  of  a  pale  yellow  color,  which,  dried,  has  a  pale 
red  tint. 
The  quantity  obtained  from  the  ethereal  solution  from  which 
the  sanguinarina  had  been  obtained,  being  very  little,  the 
original  precipitate  was  treated  with  alcohol  in  a  displacer — a 
deep  red  tincture  was  obtained.  To  this  water  was  added,  which 
caused  a  precipitate  ;  this  was  collected  on  a  filter,  dried,  and 
found  upon  examination  to  be  the  substance  sought.  The  quan- 
tity of  it  existing  in  the  root  is  but  small,  as  I  obtained,  from 
fifteen  pounds  of  the  root  operated  upon,  130  grains  of  this 
substance. 
The  dark  substance  left  after  extracting  the  Sanguinarina 
and  the  last  mentioned  body,  possesses  strong  tinctorial  proper- 
ties. It  is  soluble  in  acids,  producing  a  dark  red  compound, 
and  is  precipitated  unaltered  by  the  addition  of  an  alkali.  I 
have  not  examined  it  further. 
From  the  examination  of  this  root  it  is  evident  that  its  acrid 
and  pungent  taste  is  due  entirely  to  a  salt  of  Sanguinarina,  pro- 
bably a  chelidonate,  which  acid  (chelidonic)  I  have  obtained 
from  this  root,  the  other  two  substances  mentioned  having  but 
little  taste,  and  this  may  be  due  to  the  accidental  presence  of  a 
trace  of  the  alkaloid. 
The  red  color  of  the  root,  and  red  color  of  its  tincture  and 
other  fluid  preparations  is  not  due  entirely  to  the  Sanguinarina, 
as  all  the  other  products  have  strong  tinctorial  properties,  and 
forming  with  acids  deep  red  solutions. 
EXTRA CTUM  VVJE  URSI  ET  LUPULINiE  FLUIDUM. 
By  The  Editor. 
Dr.  W.  T.  Howard,  of  North  Carolina,  having  occasion  for 
a  preparation  which  should  combine  the  activity  of  the  two  reme- 
dies indicated  in  the  title,  suggested  that  they  might  be  prepared 
in  the  form  of  a  fluid  extract.  To  effect  this  the  following  formula 
was  adopted,  viz  : — 
Take  of  Uva  Ursi,  in  coarse  powder,  8  ounces  (Troy) 
Lupulin,  21 J  drachms  " 
White  sugar,  8  ounces  « 
Alcohol  and  water,  of  each  sufficient  quantity. 
