Am'janr,'i892arm'}  Gleanings  from  the  German  Journals.  25 
the  crude  and  purified  tuberculin,  the  examination  of  the  alcoholic 
mother-liquors  disclosed  the  substance  causing  the  difference. 
Chloroform  Pictet. — Experiments  made  to  ascertain  the  action  of 
direct  sunlight  on  this  article  proved  that  in  the  absence  of  alcohol 
it  did  not  change  by  exposure  for  three  days ;  in  the  presence  of 
alcohol  (one  per  cent.)  it  withstood  change  for  thirty  days,  although 
tested  under  most  unfavorable  conditions  (exposure  to  the  sun 
during  June  and  July).  An  examination  of  the  impurities  removed 
in  the  manufacture  of  this  chjoroform  (Am.  Jour.  Pharm.  1891,  346) 
is  in  progress.  Comment  has  been  made  upon  the  practice  of  the 
manufacturer  to  add  alcohol  to  this  purified  article,  but  this  is  to 
meet  the  requirements  of  the  German  Pharmacopoeia;  the  alcohol 
used  is  also  very  carefully  purified.  The  results  obtained  according 
to  Dr.  R.  du  Bois  Reymond  are  very  satisfactory. — Dr.  Thilo, 
Pharm.  Centralhalle,  189 1,  657  and  663. 
Thilanin  is  a  preparation  made  by  the  action  of  sulphur  upon 
lanolin  ;  it  is  intended  to  replace  thiol  and  ichthyol  in  dermal  prac- 
tice. It  contains  3  per  cent,  sulphur  and  forms  a  brownish, 
unctuous  mass  having  a  sulphur  odor.  It  is  introduced  by  Jaffe  and 
Darmstadter. — Pharm.  Centralhalle,  189 1,  678. 
New  medicinal  soaps  recommended  by  Eichhoff  are  :  1.  Menthol- 
soap  5  per  cent.,  useful  in  pruritus;  2.  Salol-soap  5  percent.,  useful 
in  obstinate  cases  of  eczema  and  psoriasis;  3.  Aristol-soap  20  per 
cent.,  also  serviceable  in  the  above  skin-diseases.  All  of  these  soaps 
should  contain  an  excess  of  fat  so  as  to  prevent  decomposition  of 
the  medicinal  ingredients. — [D.  Med.  Ztg.)  Pharm.  Centralhalle, 
1891,  679. 
Estimation  of  alkaloids  in  extracts. — Extract  of  Nux  Vomica  :  2 
gm.  of  the  triturated  extract  are  agitated  with  5  cc.  water  of  ammo- 
nia, 5  cc.  water  and  10  cc.  alcohol  until  solution  is  effected  ;  the 
solution  is  then  shaken  with  three  portions  of  chloroform,  20  cc, 
10  cc  and  10  cc.  The  united  chloroform  solutions  are  evaporated 
or  the  chloroform  distilled  off,  the  residue  warmed  upon  a  water- 
bith  for  several  minutes  with  15  cc.  ^  hydrochloric  acid,  then  fil- 
tered and  the  filter  thoroughly  washed.  The  filtrate  is  titrated 
with  -j— q-  alkali  using  cochineal  as  the  indicator  ;  if  the  number  of 
cc.  alkali  be  subtracted  from  1 50  (corresponding  to  1  5  cc.  ^L-  acid) 
and  the  remainder  multiplied  by  000364  (assuming  that  the  alka- 
