Am.  Jour.  Pharm.1 
March,  1892.  J 
Hyoscyamine  Gold  Chloride. 
119 
For  these  considerations  it  seemed  to  be  desirable  to  preserve 
drawings  of  the  crystals  of  hyoscyamine  gold  chloride  (magnified  100 
diameters),  as  obtained  by  following  the  directions  of  the  pharmaco- 
poeia. These  forms  are,  certainly,  just  as  characteristic  as  the  melt- 
ing point,  which  the  Pharmacopoeia,  perhaps  wisely,  has  omitted. 
Determinations  of  the  melting  point  are  delicate  operations,  and  I 
know  of  instances  that  physicians  have  mistaken  the  term  "  melting  " 
for  "  dissolving."  Very  slight  contaminations  (they  could  scarcely  be 
called  impurities)  with  atropine  lower  the  melting  point  of  hyoscya- 
mine gold  chloride  quite  perceptibly.  The  writer  has  observed  1 5  50, 
152°,  1 530  C.  While  such  variations  for  the  reasons  stated  are,  most 
likely,  of  no  consequence  to  the  ophthalmologist,  they  would  not 
tend  to  insure  in  the  pharmacist  a  feeling  of  absolute  reliability  in 
these  mydriatic  preparations. 
Aristol  was  applied  locally  in  certain  cases  of  cancer,  by  Dr.  E.  Arcoleo 
{Rif.  Med.,  Oct.  1891)  ;  it  relieves  pain,  arrests  bleeding,  lessens  the  discharge, 
corrects  the  offensive  odor,  and  not  being  absorbed,  has  no  toxic  action. 
Snuff  for  hay  fever — Boric  acid  2-0  gm.;  sodium  salicylate  2-5  gm.; 
cocaine  hydrochloride  0*12  gm. — Quar.  Ther.  Rev.,  Jan.,  1892. 
