142  Gleanings  from  the  German  Journals.  {AmMa°rch,i892.rm* 
taken  place  during  the  preparation  of  the  extract. — L.  van  Itallie, 
Apotheker  Ztg.}  1892,  27. 
An  antipyrine  test. — If  an  antipyrine'  solution  mixed  with  nitric 
acid  be  heated  for  some  time  there  will  develop  a  cherry-red  colora- 
tion ;  the  intensity  of  the  color  depends  upon  the  concentration  of 
the  antipyrine  solution  and  the  strength  of  the  nitric  acid  used. — 
L.  Van  Itallie,  Apotheker  Ztg.,  1892,  28. 
A  sensitive  test  for  albumin  in  urine. — The  reagent  is  made  by 
dissolving  8«o  mercuric  chloride,  4-0  tartaric  acid,  20  0  sugar  in 
200-0  water  ;  the  acid  is  added  to  produce  a  strongly  acid  solution 
and  the  sugar  to  increase  its  density.  In  applying  the  test  the  urine 
is  acidulated  with  a  few  drops  of  strong  acetic  acid,  filtered  and 
delivered  by  means  of  a  pipette  into  a  tube  half-filled  with  the 
reagent  so  as  to  form  two  layers.  If  the  urine  contains  even  less 
albumen  than  1  in  50,000,  there  is  produced  immediately  or  before 
the  lapse  of  a  minute,  a  distinct  white  ring  at  the  line  of  contact; 
the  white  ring  is  especially  seen  if  the  tube  be  held  against  a  black 
background. — Dr.  E.  Spiegler,  Oesterr.  Ztschr.f.  Pharm.,  1892,65. 
Tannate  of  quinine. — DeVrij  recommends  the  following  method 
of  preparation  :  One  part  pure  quinine  is  intimately  mixed  by  tritu- 
ration with  four  parts  tannic  acid,  ten  parts  water  added,  dried  on  a 
water-bath  at  a  temperature  not  exceeding  6o°  C,  the  residue 
powdered  and  again  dried.  The  preparation  contains  20  per  cent, 
quinine. — {Ned.  Tifds.)  Oesterr.  Ztschr.f.  Pharm.,  1892,  67. 
A  new  method  for  preparing  salol-phenyl  salicylate. — Wierp  and 
Ernert  have  recently  noticed  that  if  salicylic  acid  be  heated  to 
between  160-2400  C,  it  forms  salol  by  loss  of  water  and  carbon 
dioxide,  if  precautions  are  taken  to  remove  the  water  as  liberated 
and  prevent  access  of  air.  The  process  has  been  patented.  The 
salol  is  purified  by  washing  with  water,  or,  if  necessary,  with  soda 
solution  and  then  by  crystallization  from  alcohol  or  other  suitable 
solvent. — Pharm.  Centralhalle,  1892,  27. 
Antipyrine  and  euphorin,  when  triturated  together  liquefy  or 
become  pasty,  depending  upon  the  proportions ;  in  prescriptions  it 
has  been  found  necessary  to  dispense  the  two  separately  or  to 
enclose  the  one  prescribed  in  smaller  quantity  in  a  small  cachet  and 
then  to  enclose  this  in  a  larger  cachet  with  thet  other  ingredient 
J.  Mindes  has  noticed  that  if  the  euphorin  be  triturated  with  "s'-'gar 
