T  c;o  Ohnrpshis  /  Am,  Jour.  Pharin. 
VLevresiHb.  j      March,  1892. 
sarily  vary  considerably.  With  selected  lupulin,  using  concentrated 
ether,  I  have  obtained  70-8  per  cent.  With  acetone,  by  pushing 
the  extraction  to  completion,  I  obtained  71  per  cent.  This  latter 
of  fine  quality  was  but  slightly  soluble  in  benzin,  but  freely  in 
ether,  alcohol,  chloroform  and  glacial  acetic  acid. 
Oleoresina  Piper  is. — Ground  black  pepper  yielded  to  acetone  9-97 
per  cent.  The  piperin  soon  separated  and  was  removed  by  strain- 
ing. The  oleoresin  obtained  amounted  to  5-93  per  cent.,  and  was 
similar  to  that  obtained  by  the  use  of  ether.  It  was  but  partly 
soluble  in  benzin,  but  entirely  in  alcohol,  ether,  chloroform  and 
glacial  acetic  acid.  By  the  use  of  ether,  and  working  ona  manufac- 
turing scale,  I  have  obtained  a  yield  of  from  5  to  6-7  per  cent.,  but 
see  no  reason  why  acetone  should  not  be  substituted  for  ether  in 
this  preparation. 
Oleoresina  Zingiberis, — Powdered  Jamaica  ginger  extracted  with 
\cetone  yielded  5*57  per  cent,  of  oleoresin  of  a  fine  quality,  unsur- 
passed in  aroma  by  that  made  with  ether.  The  resincus  portion 
was  insoluble  in  benzin,  but  the  oleoresin  was  entirely  soluble  in 
ether,  alcohol,  chloroform  and  glacial  acetic  acid.  It  appeared  to  be 
identical  with  that  made  with  ether,  and  I  would  strongly  recommend 
the  use  of  acetone  in  this  preparation. 
Oleoresina  Apii  and  Apiol — An  examination  of  some  commercial 
samples  of  apiol  as  recently  made  showed  them  to  be  largely  oleo- 
resins  of  parsley  seed,  varying  in  color  from  brown  to  a  bright  green, 
and  exhibiting  great  difference  in  their  density  and  action  with  sol- 
vents. None  of  them  complied  with  the  requirements  of  an  apiol  pre- 
pared, as  originally  proposed,  by  Joret  and  Homolle  (American  Journal 
of  Pharmacy,  1 863 ,  84),  nor  according  to  the  process  of  L.  Wolff  (Ibid. 
1877,  1).  Freshly  powdered  parsley  seed  yielded  to  acetone  24  per 
cent,  of  oleoresin  from  which  3  per  cent,  of  wax  soon  separated 
leaving,  after 'straining,  21  per  cent,  of  a  bright  green  liquid  oleo- 
resin. This  was  entirely  soluble  in  ether  and  chloroform,  but  about 
10  per  cent,  of  it  of  a  resinous  character  was  insoluble  in  benzin. 
Purified  benzin  extracted  22-3  per  cent,  of  oleo-resin  entirely 
soluble  in  ether,  chloroform  and  acetone.  Both  of  these  oleoresins 
compared  favorably  with  most  of  the  so-called  "  apiols  "  of  the  market, 
and  for  this  purpose  benzin  appears  to  answer  as  well  as  ether  or 
acetone.  Upon  treating  these  oleoresins  with  alcohol  and  sub- 
sequently evaporating  this  solvent,  as  suggested  by  L.  Wolff  (loc. 
cit),  about  4  per  cent,  of  the  weight  of  the  seed  was  yielded. 
