* 
AmJu0DUe1;•li^12arm•}  Chimaphila  Umbellata.  295 
CHIMAPHILA    UMBELLATA  AND  CHIMAPHILA 
MACULATA. 
By  Josiah  C.  Peacock,  Ph.G. 
Contribution  from  the  Chemical  Laboratory  of  the  Philadelphia  College  of  Pharmacy. 
No.  109. 
This  work  was  undertaken  for  the  purpose  of  inquiring  into  the 
nature  of  the  crystalline  compound  obtained  by  distilling  Chima- 
phila umbellata  with  water,  and  to  which  the  name  Chimaphilin 
has  been  given. 
As  no  information  could  be  obtained  regarding  the  isolation  of 
this  principle  from  Chimaphila  maculata,  it  was  decided  to  examine 
it  also  in  the  same  connection.  For  this  purpose  some  of  the  last- 
named  species  was  collected  near  Haddonfield,  New  Jersey,  in 
July,  1 89 1.  The  material  collected  represented  the  plant  in  all 
stages  of  its  growth,  from  first  appearance  above  ground  to  fruiting. 
It  was  thought  desirable,  before  commencing  the  work  on  the 
special  constituent,  or  product  as  it  may  be,  to  make  a  comparative 
analysis  of  the  two  species,  and  in  view  of  the  absence  of  an  analy- 
sis of  the  species  maculata,  it  may  be  especially  useful. 
The  results  stated  below  are  for  the  leaves  separately  and  for  the 
stems  and  roots  together. 
In  each  species  the  separation  of  the  parts  was  complete. 
Percentage. 
Chimaphila  umb.       Chimaphila  mac. 
Stems  and  Stems  and 
Leaves.       Roots.      Leaves.  Roots. 
Petroleum  ether  extract,   .....  3*64  '84  2*15  73 
Stronger  ether  extract,   5*15  4-42  3*89  1*69 
Absolute  alcohol  extract,   21*09  979  17*26  6*25 
Water  extract,   n*oo  ii'47  10*45  9'9° 
Alkaline  (NaOH)  water  extract,     .  4*81  4-46  5*50  7*88 
Acidulated  (HC1)  water  extract,     .  4*50  4*20  5*80  3*60 
Starch,    .  .                                  •  1-91  3-34  2*51  3*59 
Moisture,    ............  14*60  12*80  13*00  1272 
Ash,  .   3*88  3*00  3*92  4*12 
Undetermined  (cellulose),    ....  29*42  45 '68  35 '52  49'52 
.Total,  ioo*oo  ioo*oo 
ioo*oo     100  *oo 
The  corresponding  extracts  of  like  parts  of  both  species  were 
very  similar  in  general  physical  properties. 
The  petroleum  ether  extracts  were  all  distilled  with  water 
whereby  crystals  of  chimaphilin  were  obtained. 
