412  Constituents  of  Angostura  Bark.  {Aml^Z'&rm' 
very  sparingly  soluble  in  water  ;  it  melts  at  1820.  The  metliiodidc, 
C19H19N03,MeI,  forms  a  fine,  yellow,  crystalline  powder,  readily 
soluble  in  hot  water  and  alcohol;  it  melts  at  1420,  and  has  an 
intensely  bitter  taste. 
Cusparine,  C2oH19N03  is  comparatively  easily  separated  from  the 
other  bases,  owing  to  the  sparing  solubility  of  its  salts.  It  melts  at 
890,  and  is  readily  soluble  in  alcohol,  ether,  chloroform,  acetone 
and  benzene,  more  sparingly  in  light  petroleum.  Its  salts  are  white 
and  sparingly  soluble  in  water,  more  readily  in  alcohol.  The 
hydrochloride,  C20H19NO3,HCl  -j-  3H20,  crystallizes  in  long,  white 
needles,  very  slightly  soluble  in  water,  readily  in  alcohol,  and  of  a 
bitter  taste ;  the  hydrobromide,  C20H19NO3,HBr,  forms  long,  pale-yel- 
low needles,  of  bitter  taste;  it  is  very  sparingly  soluble  in  water; 
the  sulphate,  (C20H19NO3)2,H2SO4  +  yH20,  crystallizes  in  white 
prisms  of  a  bitter  taste  ;  it  is  only  sparingly  soluble  in  water,  more 
readily  in  alcohol ;  the  aurochloride,  C20H19NO3,HAuCl4,  forms  a  light- 
brown,  voluminous  mass  of  minute  crystals,  melts  at  1 65 0 ,  and  it  is 
almost  insoluble  in  water  ;  the  platinochloride ;  (C20H19NO3)2,  H2PtCl6, 
forms  minute,  yellow  needles,  which  may  be  recrystallized  from  hot 
water.  It  melts  at  1/9°.  The  methiodide,  C20H19NO3MeI,  forms 
lustrous,  yellow  needles,  of  intensely  bitter  taste,  melting  at  1860. 
Cusparidine,  C19H17N03,  crystallizes  from  light  petroleum  in  mi- 
nute, slender,  white  needles.  It  melts  at  780,  and  dissolves  readily 
in  chloroform,  alcohol,  ether,  and  ethyl  acetate,  less  readily  in  light 
petroleum.  The  salts  are  white  and  of  bitter  taste;  they  are  less 
soluble  than  those  of  galipine  and  galipidine,  but  more  readily  than 
those  of  cusparine.  The  hydrochloride,  C19H17N03,HC1  -f-  3H20,  is 
precipitated  as  a  white,  voluminous  mass  of  crystals,  which  melt 
very  readily  ;  it  is  sparingly  soluble  in  water,  more  readily  in  alcohol, 
and  has  a  bitter  taste;  the  hydrobromide,  C19H17N03,HBr,  crystallizes 
from  water  in  well-formed  prisms,  which  are  anhydrous  ;  it  is  spar- 
ingly soluble  in  hot  water,  almost  insoluble  in  cold  water,  more 
readily  soluble  in  alcohol.  The  sulphate,  (C19H]7N03)2,H2S04 
-f-  3H20,  separates  as  a  crystalline  precipitate  when  cusparidine  is 
exactly  neutralized  with  sulphuric  acid  ;  it  is  moderately  soluble  in 
water,  still  more  readily  in  alcohol,  and  has  a  very  bitter  taste.  The 
aurochloride,  C19H17N03,HAuCl4,  separates  as  a  voluminous,  brown 
mass  of  minute  crystals;  it  is  anhydrous,  and  melts  at  1670.  The 
platinochloride,  (C19H17N03)2,H2PtCl6,  forms  a  pale-yellow,  crystal- 
