Amoc0tu!"i8P9?arm'}  Gillenia  Stipulacea.  5*3 
These  figures  would  indicate  that  the  formula  is  C20H25O36HNO3, 
which  would  require  the  following  as  the  theoretical  composition. 
C — 26  49  per  cent.       H — 276  per  cent.       O — 64  per  cent. 
N — 1-54  per  cent.  ==  HNOs — 6  96  per  cent. 
GILLENIA  STIPULACEA,  NUTTALL. 
By  Gordon  L.  Curry,  Ph.g. 
From  a  thesis  presented  to  the  Louisville  College  of  Pharmacy, 
and  published  in  the  American  Practitioner  and  News,  May  7,  1892, 
p.  294-298,  we  make  the  following  abstract  relating  to  the  analysis 
of  the  subterraneous  organs  which,  on  drying  finally  in  a  hot-air 
oven,  lost  42-9,  and  in  another  experiment  35'9per  cent,  of  moisture; 
on  incineration  10  gm.  of  the  powder  left  0-16  gm.  ash. 
Benzene  extracted  from  20  gm.  of  the  powder  0-30  gm.  fat, 
partly  liquid.  The  ethereal  extract  subsequently  obtained  was 
partly — about  one-third — soluble  in  water,  and  nearly  two  thirds 
soluble  in  alcohol,  both  solutions  being  bitter,  but  free  from  alka- 
loids. For  the  isolation  of  the  bitter  principles,  200  cc.  of  infusion 
were  prepared  from  20  gm.  of  the  powdered  drug  with  hot  distilled 
water,  and  the  liquid  agitated  with  ether. 
The  ethereal  liquid  was  evaporated  in  a  beaker  glass  and  at  a 
low  temperature,  leaving  a  small  amount. of  slightly  yellowish 
crystalline  residue.  A  portion  of  this  residue,  on  being  dissolved 
in  acidulated  water,  decomposed  Fehling's  solution  very  readily. 
The  remainder  of  the  residue  was  dissolved  in  water,  treated  with 
ether,  and  the  ethereal  layer  evaporated  yielding  a  small  amount  of 
white,  feathery  crystals,  soluble  in  water,  alcohol,  and  dilute  acids. 
After  boiling  with  sulphuric  acid  and  treating  with  Fehling's  solu- 
tion, a  reduction  of  the  copper  immediately  ensued.  Other  tests 
for  glucosides  produced  positive  results.  The  glucoside  is  colored 
red  by  sulphuric  acid ;  yellow  by  nitric  acid,  and  deepens  the  color 
of  chromic  acid.  The  author  proposes  the  name  gillein  for  this 
body,  which  in  the  dose  of  \  grain  was  observed  to  produce  nausea, 
approaching  emetic  action. 
The  aqueous  infusion  after  having  been  treated  with  ether, 
deposited  in  a  few  days  a  pinkish  powder,  brown  after  drying, 
insoluble  in  alcohol  and  water,  of  a  bitter  taste,  and  colored  different 
shades  of  yellow  with  the  reagents  named  above.  The  sherry-colored 
